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Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication.
Prestwich RJ, Ilett EJ, Errington F, Diaz RM, Steele LP, Kottke T, Thompson J, Galivo F, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA. Prestwich RJ, et al. Among authors: vile rg. Clin Cancer Res. 2009 Jul 1;15(13):4374-4381. doi: 10.1158/1078-0432.CCR-09-0334. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509134 Free PMC article.
Genetic prodrug activation therapy.
Martin LA, Vile R, Lemoine NR, Sikora K, Pandha HS. Martin LA, et al. Lancet. 1997 Dec 20-27;350(9094):1793-4. doi: 10.1016/s0140-6736(05)63633-1. Lancet. 1997. PMID: 9428248 No abstract available.
Gene therapy for cancer--managing expectations.
Melcher AA, Garcia-Ribas I, Vile RG. Melcher AA, et al. Among authors: vile rg. BMJ. 1997 Dec 13;315(7122):1604-7. doi: 10.1136/bmj.315.7122.1604. BMJ. 1997. PMID: 9437283 Free PMC article. Review. No abstract available.
300 results