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Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication.
Prestwich RJ, Ilett EJ, Errington F, Diaz RM, Steele LP, Kottke T, Thompson J, Galivo F, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA. Prestwich RJ, et al. Among authors: errington f. Clin Cancer Res. 2009 Jul 1;15(13):4374-4381. doi: 10.1158/1078-0432.CCR-09-0334. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509134 Free PMC article.
Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial.
White CL, Twigger KR, Vidal L, De Bono JS, Coffey M, Heinemann L, Morgan R, Merrick A, Errington F, Vile RG, Melcher AA, Pandha HS, Harrington KJ. White CL, et al. Among authors: errington f. Gene Ther. 2008 Jun;15(12):911-20. doi: 10.1038/gt.2008.21. Epub 2008 Mar 6. Gene Ther. 2008. PMID: 18323793 Clinical Trial.
Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy.
Twigger K, Vidal L, White CL, De Bono JS, Bhide S, Coffey M, Thompson B, Vile RG, Heinemann L, Pandha HS, Errington F, Melcher AA, Harrington KJ. Twigger K, et al. Among authors: errington f. Clin Cancer Res. 2008 Feb 1;14(3):912-23. doi: 10.1158/1078-0432.CCR-07-1400. Clin Cancer Res. 2008. PMID: 18245555
Oncolytic viruses: a novel form of immunotherapy.
Prestwich RJ, Harrington KJ, Pandha HS, Vile RG, Melcher AA, Errington F. Prestwich RJ, et al. Among authors: errington f. Expert Rev Anticancer Ther. 2008 Oct;8(10):1581-8. doi: 10.1586/14737140.8.10.1581. Expert Rev Anticancer Ther. 2008. PMID: 18925850 Free PMC article. Review.
Tumor infection by oncolytic reovirus primes adaptive antitumor immunity.
Prestwich RJ, Errington F, Ilett EJ, Morgan RS, Scott KJ, Kottke T, Thompson J, Morrison EE, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA. Prestwich RJ, et al. Among authors: errington f. Clin Cancer Res. 2008 Nov 15;14(22):7358-66. doi: 10.1158/1078-0432.CCR-08-0831. Clin Cancer Res. 2008. PMID: 19010851 Free PMC article.
31 results