Nielsen EI - Search Results

1

Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study.

Nielsen EI, Sandström M, Honoré PH, Ewald U, Friberg LE. Nielsen EI, et al. Clin Pharmacokinet. 2009;48(4):253-63. doi: 10.2165/00003088-200948040-00003. Clin Pharmacokinet. 2009. PMID: 19492870 Clinical Trial.

2

Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments.

Nielsen EI, Viberg A, Löwdin E, Cars O, Karlsson MO, Sandström M. Nielsen EI, et al. Antimicrob Agents Chemother. 2007 Jan;51(1):128-36. doi: 10.1128/AAC.00604-06. Epub 2006 Oct 23. Antimicrob Agents Chemother. 2007. PMID: 17060524 Free PMC article.

3

Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1571-9. doi: 10.1128/AAC.01286-10. Epub 2011 Jan 31. Antimicrob Agents Chemother. 2011. PMID: 21282424 Free PMC article.

4

Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Antimicrob Agents Chemother. 2011 Oct;55(10):4619-30. doi: 10.1128/AAC.00182-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807983 Free PMC article.

5

Pharmacokinetic-pharmacodynamic model for gentamicin and its adaptive resistance with predictions of dosing schedules in newborn infants.

Mohamed AF, Nielsen EI, Cars O, Friberg LE. Mohamed AF, et al. Among authors: nielsen ei. Antimicrob Agents Chemother. 2012 Jan;56(1):179-88. doi: 10.1128/AAC.00694-11. Epub 2011 Oct 28. Antimicrob Agents Chemother. 2012. PMID: 22037853 Free PMC article.

6

Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs.

Nielsen EI, Friberg LE. Nielsen EI, et al. Pharmacol Rev. 2013 Jun 26;65(3):1053-90. doi: 10.1124/pr.111.005769. Print 2013 Jul. Pharmacol Rev. 2013. PMID: 23803529 Review.

7

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants.

Khan DD, Lagerbäck P, Cao S, Lustig U, Nielsen EI, Cars O, Hughes D, Andersson DI, Friberg LE. Khan DD, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2015 Nov;70(11):3051-60. doi: 10.1093/jac/dkv233. Epub 2015 Sep 7. J Antimicrob Chemother. 2015. PMID: 26349518

8

Simulation-Based Evaluation of PK/PD Indices for Meropenem Across Patient Groups and Experimental Designs.

Kristoffersson AN, David-Pierson P, Parrott NJ, Kuhlmann O, Lave T, Friberg LE, Nielsen EI. Kristoffersson AN, et al. Among authors: nielsen ei. Pharm Res. 2016 May;33(5):1115-25. doi: 10.1007/s11095-016-1856-x. Epub 2016 Jan 19. Pharm Res. 2016. PMID: 26786016

9

Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK/PD model.

Mohamed AF, Kristoffersson AN, Karvanen M, Nielsen EI, Cars O, Friberg LE. Mohamed AF, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2016 May;71(5):1279-90. doi: 10.1093/jac/dkv488. Epub 2016 Feb 4. J Antimicrob Chemother. 2016. PMID: 26850719

10

A pharmacokinetic-pharmacodynamic (PKPD) model based on in vitro time-kill data predicts the in vivo PK/PD index of colistin.

Khan DD, Friberg LE, Nielsen EI. Khan DD, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2016 Jul;71(7):1881-4. doi: 10.1093/jac/dkw057. Epub 2016 Mar 16. J Antimicrob Chemother. 2016. PMID: 26983860

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