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Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer.
Tutt ANJ, Garber JE, Kaufman B, Viale G, Fumagalli D, Rastogi P, Gelber RD, de Azambuja E, Fielding A, Balmaña J, Domchek SM, Gelmon KA, Hollingsworth SJ, Korde LA, Linderholm B, Bandos H, Senkus E, Suga JM, Shao Z, Pippas AW, Nowecki Z, Huzarski T, Ganz PA, Lucas PC, Baker N, Loibl S, McConnell R, Piccart M, Schmutzler R, Steger GG, Costantino JP, Arahmani A, Wolmark N, McFadden E, Karantza V, Lakhani SR, Yothers G, Campbell C, Geyer CE Jr; OlympiA Clinical Trial Steering Committee and Investigators. Tutt ANJ, et al. N Engl J Med. 2021 Jun 24;384(25):2394-2405. doi: 10.1056/NEJMoa2105215. Epub 2021 Jun 3. N Engl J Med. 2021. PMID: 34081848 Free PMC article. Clinical Trial.
Green Light Activated Dual-Action Pt(IV) Prodrug With Enhanced PDT activity.
Krasnovskaya OO, Spector D, Bykusov V, Isaeva Y, Grishin Y, Akasov R, Zharova A, Rodin I, Kuzmin V, Vokuev M, Nikitina V, Martynov A, Beloglazkina E. Krasnovskaya OO, et al. Among authors: spector d. ChemMedChem. 2025 Jan 10:e202400786. doi: 10.1002/cmdc.202400786. Online ahead of print. ChemMedChem. 2025. PMID: 39791228
Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome.
East MP, Sprung RW, Okumu DO, Olivares-Quintero JF, Joisa CU, Chen X, Zhang Q, Erdmann-Gilmore P, Mi Y, Sciaky N, Malone JP, Bhatia S, McCabe IC, Xu Y, Sutcliffe MD, Luo J, Spears PA, Perou CM, Earp HS, Carey LA, Yeh JJ, Spector DL, Gomez SM, Spanheimer PM, Townsend RR, Johnson GL. East MP, et al. Among authors: spector dl. bioRxiv [Preprint]. 2024 Oct 4:2024.10.04.614143. doi: 10.1101/2024.10.04.614143. bioRxiv. 2024. PMID: 39464086 Free PMC article. Preprint.
On the optical response of novel coumarin-fused NIR BODIPY dyes to X-rays.
Lifanovsky N, Spector D, Egorov A, Mazur D, Bubley A, Belousov A, Klimovich M, Kostyukov A, Kolyvanova M, Beloglazkina E, Kuzmin V, Krasnovskaya O, Morozov V. Lifanovsky N, et al. Among authors: spector d. Spectrochim Acta A Mol Biomol Spectrosc. 2025 Feb 5;326:125227. doi: 10.1016/j.saa.2024.125227. Epub 2024 Sep 27. Spectrochim Acta A Mol Biomol Spectrosc. 2025. PMID: 39383547
MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer.
Klingbeil O, Skopelitis D, Tonelli C, Yoshimoto T, Alpsoy A, Panepinto MC, Minicozzi F, Merrill JR, Cafiero AM, Aggarwal D, Russo S, Ha T, Demerdash OE, Wee TL, Spector DL, Lyons SK, Tuveson DA, Cifani P, Vakoc CR. Klingbeil O, et al. Among authors: spector dl. Cancer Discov. 2024 Dec 2;14(12):2471-2488. doi: 10.1158/2159-8290.CD-23-1529. Cancer Discov. 2024. PMID: 39058094 Free PMC article.
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Cunniff PJ, Schier AC, Skopelitis D, Trousdell MC, Moresco P, Gao Y, Kechejian V, He XY, Sahin Y, Wan L, Alpsoy A, Liverpool J, Krainer AR, Egeblad M, Spector DL, Fearon DT, Dos Santos CO, Taatjes DJ, Vakoc CR. Maia-Silva D, et al. Among authors: spector dl. Nat Genet. 2024 Jul;56(7):1377-1385. doi: 10.1038/s41588-024-01790-y. Epub 2024 Jun 17. Nat Genet. 2024. PMID: 38886586
483 results