Kuwano Y - Search Results

1

The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.

Costantino CL, Witkiewicz AK, Kuwano Y, Cozzitorto JA, Kennedy EP, Dasgupta A, Keen JC, Yeo CJ, Gorospe M, Brody JR. Costantino CL, et al. Among authors: kuwano y. Cancer Res. 2009 Jun 1;69(11):4567-72. doi: 10.1158/0008-5472.CAN-09-0371. Cancer Res. 2009. PMID: 19487279 Free PMC article.

2

The mRNA-destabilizing protein tristetraprolin is suppressed in many cancers, altering tumorigenic phenotypes and patient prognosis.

Brennan SE, Kuwano Y, Alkharouf N, Blackshear PJ, Gorospe M, Wilson GM. Brennan SE, et al. Among authors: kuwano y. Cancer Res. 2009 Jun 15;69(12):5168-76. doi: 10.1158/0008-5472.CAN-08-4238. Epub 2009 Jun 2. Cancer Res. 2009. PMID: 19491267 Free PMC article.

3

The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer.

Calaluce R, Gubin MM, Davis JW, Magee JD, Chen J, Kuwano Y, Gorospe M, Atasoy U. Calaluce R, et al. Among authors: kuwano y. BMC Cancer. 2010 Apr 6;10:126. doi: 10.1186/1471-2407-10-126. BMC Cancer. 2010. PMID: 20370918 Free PMC article.

4

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels.

Abdelmohsen K, Srikantan S, Kuwano Y, Gorospe M. Abdelmohsen K, et al. Among authors: kuwano y. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20297-302. doi: 10.1073/pnas.0809376106. Epub 2008 Dec 16. Proc Natl Acad Sci U S A. 2008. PMID: 19088191 Free PMC article.

5

Protecting the stress response, guarding the MKP-1 mRNA.

Kuwano Y, Gorospe M. Kuwano Y, et al. Cell Cycle. 2008 Sep 1;7(17):2640-2. doi: 10.4161/cc.7.17.6534. Epub 2008 Sep 2. Cell Cycle. 2008. PMID: 18728392 Free PMC article. Review.

6

MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90.

Kuwano Y, Kim HH, Abdelmohsen K, Pullmann R Jr, Martindale JL, Yang X, Gorospe M. Kuwano Y, et al. Mol Cell Biol. 2008 Jul;28(14):4562-75. doi: 10.1128/MCB.00165-08. Epub 2008 May 19. Mol Cell Biol. 2008. PMID: 18490444 Free PMC article.

7

Modification at HuR(S242) alters HuR localization and proliferative influence.

Kim HH, Yang X, Kuwano Y, Gorospe M. Kim HH, et al. Among authors: kuwano y. Cell Cycle. 2008 Nov 1;7(21):3371-7. doi: 10.4161/cc.7.21.6895. Epub 2008 Nov 1. Cell Cycle. 2008. PMID: 18948743 Free PMC article.

8

Analysis of nitric oxide-stabilized mRNAs in human fibroblasts reveals HuR-dependent heme oxygenase 1 upregulation.

Kuwano Y, Rabinovic A, Srikantan S, Gorospe M, Demple B. Kuwano Y, et al. Mol Cell Biol. 2009 May;29(10):2622-35. doi: 10.1128/MCB.01495-08. Epub 2009 Mar 16. Mol Cell Biol. 2009. PMID: 19289500 Free PMC article.

9

Ubiquitin-mediated proteolysis of HuR by heat shock.

Abdelmohsen K, Srikantan S, Yang X, Lal A, Kim HH, Kuwano Y, Galban S, Becker KG, Kamara D, de Cabo R, Gorospe M. Abdelmohsen K, et al. Among authors: kuwano y. EMBO J. 2009 May 6;28(9):1271-82. doi: 10.1038/emboj.2009.67. Epub 2009 Mar 26. EMBO J. 2009. PMID: 19322201 Free PMC article.

10

HuR recruits let-7/RISC to repress c-Myc expression.

Kim HH, Kuwano Y, Srikantan S, Lee EK, Martindale JL, Gorospe M. Kim HH, et al. Among authors: kuwano y. Genes Dev. 2009 Aug 1;23(15):1743-8. doi: 10.1101/gad.1812509. Epub 2009 Jul 2. Genes Dev. 2009. PMID: 19574298 Free PMC article.

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