Chen SH - Search Results

1

Bicyclic cyanothiazolidines as novel dipeptidyl peptidase 4 inhibitors.

Betancort JM, Winn DT, Liu R, Xu Q, Liu J, Liao W, Chen SH, Carney D, Hanway D, Schmeits J, Li X, Gordon E, Campbell DA. Betancort JM, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4437-40. doi: 10.1016/j.bmcl.2009.05.048. Epub 2009 May 18. Bioorg Med Chem Lett. 2009. PMID: 19482472

2

Bis-S-acyl-2-thioethyl (SATE)-bearing monophosphate prodrug of beta-L-FD4C as potent anti-HBV agent.

Li X, Carmichael E, Feng M, King I, Doyle TW, Chen SH. Li X, et al. Among authors: chen sh. Bioorg Med Chem Lett. 1998 Jan 6;8(1):57-62. doi: 10.1016/s0960-894x(97)10178-0. Bioorg Med Chem Lett. 1998. PMID: 9871628

3

Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors.

Chen SH, Lamar J, Victor F, Snyder N, Johnson R, Heinz BA, Wakulchik M, Wang QM. Chen SH, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3531-6. doi: 10.1016/s0960-894x(03)00753-4. Bioorg Med Chem Lett. 2003. PMID: 14505664

4

Discovery of a novel bicycloproline P2 bearing peptidyl alpha-ketoamide LY514962 as HCV protease inhibitor.

Yip Y, Victor F, Lamar J, Johnson R, Wang QM, Barket D, Glass J, Jin L, Liu L, Venable D, Wakulchik M, Xie C, Heinz B, Villarreal E, Colacino J, Yumibe N, Tebbe M, Munroe J, Chen SH. Yip Y, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2004 Jan 5;14(1):251-6. doi: 10.1016/j.bmcl.2003.09.074. Bioorg Med Chem Lett. 2004. PMID: 14684337

5

Phe*-Ala-based pentapeptide mimetics are BACE inhibitors: P2 and P3 SAR.

Lamar J, Hu J, Bueno AB, Yang HC, Guo D, Copp JD, McGee J, Gitter B, Timm D, May P, McCarthy J, Chen SH. Lamar J, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2004 Jan 5;14(1):239-43. doi: 10.1016/j.bmcl.2003.09.084. Bioorg Med Chem Lett. 2004. PMID: 14684335

6

Novel P4 truncated tripeptidyl alpha-ketoamides as HCV protease inhibitors.

Lamar J, Victor F, Snyder N, Johnson RB, Wang QM, Glass JI, Chen SH. Lamar J, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2004 Jan 5;14(1):263-6. doi: 10.1016/j.bmcl.2003.09.076. Bioorg Med Chem Lett. 2004. PMID: 14684339

7

Synthesis and biological evaluation of novel C-4 aziridine-bearing paclitaxel (taxol) analogs.

Chen SH, Fairchild C, Long BH. Chen SH, et al. J Med Chem. 1995 Jun 9;38(12):2263-7. doi: 10.1021/jm00012a029. J Med Chem. 1995. PMID: 7783160

8

Syntheses and antifungal activities of novel 3-amido bearing pseudomycin analogues.

Zhang YZ, Sun X, Zeckner DJ, Sachs RK, Current WL, Gidda J, Rodriguez M, Chen SH. Zhang YZ, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2001 Apr 9;11(7):903-7. doi: 10.1016/s0960-894x(01)00101-9. Bioorg Med Chem Lett. 2001. PMID: 11294388

9

Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues.

Xue M, Long BH, Fairchild C, Johnston K, Rose WC, Kadow JF, Vyas DM, Chen SH. Xue M, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2000 Jun 19;10(12):1327-31. doi: 10.1016/s0960-894x(00)00242-0. Bioorg Med Chem Lett. 2000. PMID: 10890157

10

P4 cap modified tetrapeptidyl alpha-ketoamides as potent HCV NS3 protease inhibitors.

Sun DX, Liu L, Heinz B, Kolykhalov A, Lamar J, Johnson RB, Wang QM, Yip Y, Chen SH. Sun DX, et al. Among authors: chen sh. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4333-8. doi: 10.1016/j.bmcl.2004.05.078. Bioorg Med Chem Lett. 2004. PMID: 15261297

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