Howell AR - Search Results

1

Synthesis and evaluation of an acyl-chain unsaturated analog of the Th2 biasing, immunostimulatory glycolipid, OCH.

Velmourougane G, Raju R, Bricard G, Im JS, Besra GS, Porcelli SA, Howell AR. Velmourougane G, et al. Among authors: howell ar. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3386-8. doi: 10.1016/j.bmcl.2009.05.042. Epub 2009 May 18. Bioorg Med Chem Lett. 2009. PMID: 19481452 Free PMC article.

2

The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.

Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. Sidobre S, et al. Among authors: howell ar. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12254-9. doi: 10.1073/pnas.0404632101. Epub 2004 Aug 10. Proc Natl Acad Sci U S A. 2004. PMID: 15304644 Free PMC article.

3

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.

Ndonye RM, Izmirian DP, Dunn MF, Yu KO, Porcelli SA, Khurana A, Kronenberg M, Richardson SK, Howell AR. Ndonye RM, et al. Among authors: howell ar. J Org Chem. 2005 Dec 9;70(25):10260-70. doi: 10.1021/jo051147h. J Org Chem. 2005. PMID: 16323834

4

Cross metathesis with strained exocyclic enones: synthesis of 3-alkylideneoxetan-2-ones from 3-methyleneoxetan-2-ones.

Raju R, Howell AR. Raju R, et al. Among authors: howell ar. Org Lett. 2006 May 11;8(10):2139-41. doi: 10.1021/ol060624v. Org Lett. 2006. PMID: 16671801

5

Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator.

Forestier C, Takaki T, Molano A, Im JS, Baine I, Jerud ES, Illarionov P, Ndonye R, Howell AR, Santamaria P, Besra GS, Dilorenzo TP, Porcelli SA. Forestier C, et al. Among authors: howell ar. J Immunol. 2007 Feb 1;178(3):1415-25. doi: 10.4049/jimmunol.178.3.1415. J Immunol. 2007. PMID: 17237389

6

Cross metathesis of alpha-methylene lactones II: gamma- and delta-lactones.

Raju R, Allen LJ, Le T, Taylor CD, Howell AR. Raju R, et al. Among authors: howell ar. Org Lett. 2007 Apr 26;9(9):1699-701. doi: 10.1021/ol070574+. Epub 2007 Apr 4. Org Lett. 2007. PMID: 17407303

7

Production and characterization of monoclonal antibodies against complexes of the NKT cell ligand alpha-galactosylceramide bound to mouse CD1d.

Yu KO, Im JS, Illarionov PA, Ndonye RM, Howell AR, Besra GS, Porcelli SA. Yu KO, et al. Among authors: howell ar. J Immunol Methods. 2007 May 31;323(1):11-23. doi: 10.1016/j.jim.2007.03.006. Epub 2007 Apr 5. J Immunol Methods. 2007. PMID: 17442335 Free PMC article.

8

Rapid identification of immunostimulatory alpha-galactosylceramides using synthetic combinatorial libraries.

Li Q, Ndonye RM, Illarionov PA, Yu KO, Jerud ES, Diaz K, Bricard G, Porcelli SA, Besra GS, Chang YT, Howell AR. Li Q, et al. Among authors: howell ar. J Comb Chem. 2007 Nov-Dec;9(6):1084-93. doi: 10.1021/cc070057i. Epub 2007 Sep 27. J Comb Chem. 2007. PMID: 17896821

9

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.

Kinjo Y, Pei B, Bufali S, Raju R, Richardson SK, Imamura M, Fujio M, Wu D, Khurana A, Kawahara K, Wong CH, Howell AR, Seeberger PH, Kronenberg M. Kinjo Y, et al. Among authors: howell ar. Chem Biol. 2008 Jul 21;15(7):654-64. doi: 10.1016/j.chembiol.2008.05.012. Chem Biol. 2008. PMID: 18635002 Free PMC article.

10

Natural killer T-cell autoreactivity leads to a specialized activation state.

Wang X, Chen X, Rodenkirch L, Simonson W, Wernimont S, Ndonye RM, Veerapen N, Gibson D, Howell AR, Besra GS, Painter GF, Huttenlocher A, Gumperz JE. Wang X, et al. Among authors: howell ar. Blood. 2008 Nov 15;112(10):4128-38. doi: 10.1182/blood-2008-05-157529. Epub 2008 Sep 8. Blood. 2008. PMID: 18779390 Free PMC article.

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