Robertson GR - Search Results

1

A novel approach to investigate the subcellular distribution of nuclear receptors in vivo.

Matic M, Nakhel S, Lehnert AM, Polly P, Clarke SJ, Robertson GR. Matic M, et al. Among authors: robertson gr. Nucl Recept Signal. 2009 May 8;7:e004. doi: 10.1621/nrs.07004. Nucl Recept Signal. 2009. PMID: 19471583 Free PMC article.

2

The alternatively spliced murine pregnane X receptor isoform, mPXR(delta171-211) exhibits a repressive action.

Matic M, Corradin AP, Tsoli M, Clarke SJ, Polly P, Robertson GR. Matic M, et al. Among authors: robertson gr. Int J Biochem Cell Biol. 2010 May;42(5):672-82. doi: 10.1016/j.biocel.2010.01.001. Epub 2010 Jan 11. Int J Biochem Cell Biol. 2010. PMID: 20060928

3

Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.

Kacevska M, Downes MR, Sharma R, Evans RM, Clarke SJ, Liddle C, Robertson GR. Kacevska M, et al. Among authors: robertson gr. Clin Cancer Res. 2011 May 15;17(10):3170-80. doi: 10.1158/1078-0432.CCR-10-3289. Epub 2011 Apr 15. Clin Cancer Res. 2011. PMID: 21498392 Free PMC article.

4

Pregnane X receptor: promiscuous regulator of detoxification pathways.

Matic M, Mahns A, Tsoli M, Corradin A, Polly P, Robertson GR. Matic M, et al. Among authors: robertson gr. Int J Biochem Cell Biol. 2007;39(3):478-83. doi: 10.1016/j.biocel.2006.08.017. Epub 2006 Sep 14. Int J Biochem Cell Biol. 2007. PMID: 17188925 Review.

5

Transgenic mouse models of human CYP3A4 gene regulation.

Robertson GR, Field J, Goodwin B, Bierach S, Tran M, Lehnert A, Liddle C. Robertson GR, et al. Mol Pharmacol. 2003 Jul;64(1):42-50. doi: 10.1124/mol.64.1.42. Mol Pharmacol. 2003. PMID: 12815159

6

Inflammation and altered drug clearance in cancer: transcriptional repression of a human CYP3A4 transgene in tumor-bearing mice.

Robertson GR, Liddle C, Clarke SJ. Robertson GR, et al. Clin Pharmacol Ther. 2008 Jun;83(6):894-7. doi: 10.1038/clpt.2008.55. Epub 2008 Mar 26. Clin Pharmacol Ther. 2008. PMID: 18388870 Review.

7

Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer.

Charles KA, Rivory LP, Brown SL, Liddle C, Clarke SJ, Robertson GR. Charles KA, et al. Among authors: robertson gr. Clin Cancer Res. 2006 Dec 15;12(24):7492-7. doi: 10.1158/1078-0432.CCR-06-0023. Clin Cancer Res. 2006. PMID: 17189422

8

Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched historical control study.

Jankova L, Robertson G, Chan C, Tan KL, Kohonen-Corish M, Fung CL, Clarke C, Lin BP, Molloy M, Chapuis PH, Bokey L, Dent OF, Clarke SJ. Jankova L, et al. BMC Cancer. 2012 May 28;12:196. doi: 10.1186/1471-2407-12-196. BMC Cancer. 2012. PMID: 22639861 Free PMC article.

9

Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing.

Kacevska M, Robertson GR, Clarke SJ, Liddle C. Kacevska M, et al. Among authors: robertson gr. Expert Opin Drug Metab Toxicol. 2008 Feb;4(2):137-49. doi: 10.1517/17425255.4.2.137. Expert Opin Drug Metab Toxicol. 2008. PMID: 18248309 Review.

10

Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice.

Tsoli M, Moore M, Burg D, Painter A, Taylor R, Lockie SH, Turner N, Warren A, Cooney G, Oldfield B, Clarke S, Robertson G. Tsoli M, et al. Cancer Res. 2012 Sep 1;72(17):4372-82. doi: 10.1158/0008-5472.CAN-11-3536. Epub 2012 Jun 19. Cancer Res. 2012. PMID: 22719069

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