Roth BL - Search Results

1

Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.

Hwang JY, Arnold LA, Zhu F, Kosinski A, Mangano TJ, Setola V, Roth BL, Guy RK. Hwang JY, et al. Among authors: roth bl. J Med Chem. 2009 Jul 9;52(13):3892-901. doi: 10.1021/jm9002704. J Med Chem. 2009. PMID: 19469546 Free PMC article.

2

N1-benzenesulfonylgramine and N1-benzenesulfonylskatole: novel 5-HT6 receptor ligand templates.

Pullagurla MR, Dukat M, Setola V, Roth B, Glennon RA. Pullagurla MR, et al. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3355-9. doi: 10.1016/s0960-894x(03)00612-7. Bioorg Med Chem Lett. 2003. PMID: 12951125

3

Why mice are neither miniature humans nor small rats: a cautionary tale involving 5-hydroxytryptamine-6 serotonin receptor species variants.

Setola V, Roth BL. Setola V, et al. Among authors: roth bl. Mol Pharmacol. 2003 Dec;64(6):1277-8. doi: 10.1124/mol.64.6.1277. Mol Pharmacol. 2003. PMID: 14645656 Review. No abstract available.

4

1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands.

Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. Chang-Fong J, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1961-4. doi: 10.1016/j.bmcl.2004.01.071. Bioorg Med Chem Lett. 2004. PMID: 15050637

5

Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor.

Setola V, Dukat M, Glennon RA, Roth BL. Setola V, et al. Among authors: roth bl. Mol Pharmacol. 2005 Jul;68(1):20-33. doi: 10.1124/mol.104.009266. Epub 2005 Apr 14. Mol Pharmacol. 2005. PMID: 15831837

6

Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.

Pullagurla M, Siripurapu U, Kolanos R, Bondarev ML, Dukat M, Setola V, Roth BL, Glennon RA. Pullagurla M, et al. Among authors: roth bl. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5298-302. doi: 10.1016/j.bmcl.2005.08.059. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183286

7

Screening the receptorome reveals molecular targets responsible for drug-induced side effects: focus on 'fen-phen'.

Setola V, Roth BL. Setola V, et al. Among authors: roth bl. Expert Opin Drug Metab Toxicol. 2005 Oct;1(3):377-87. doi: 10.1517/17425255.1.3.377. Expert Opin Drug Metab Toxicol. 2005. PMID: 16863450 Review.

8

Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.

Sikazwe DM, Nkansah NT, Altundas R, Zhu XY, Roth BL, Setola V, Ablordeppey SY. Sikazwe DM, et al. Among authors: roth bl. Bioorg Med Chem. 2009 Feb 15;17(4):1716-23. doi: 10.1016/j.bmc.2008.12.054. Epub 2008 Dec 31. Bioorg Med Chem. 2009. PMID: 19155177 Free PMC article.

9

Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil.

Zolkowska D, Jain R, Rothman RB, Partilla JS, Roth BL, Setola V, Prisinzano TE, Baumann MH. Zolkowska D, et al. Among authors: roth bl. J Pharmacol Exp Ther. 2009 May;329(2):738-46. doi: 10.1124/jpet.108.146142. Epub 2009 Feb 5. J Pharmacol Exp Ther. 2009. PMID: 19197004 Free PMC article.

10

Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2).

Kimple AJ, Soundararajan M, Hutsell SQ, Roos AK, Urban DJ, Setola V, Temple BR, Roth BL, Knapp S, Willard FS, Siderovski DP. Kimple AJ, et al. Among authors: roth bl. J Biol Chem. 2009 Jul 17;284(29):19402-11. doi: 10.1074/jbc.M109.024711. Epub 2009 May 28. J Biol Chem. 2009. PMID: 19478087 Free PMC article.

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