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Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors.
Wüller S, Wiesner B, Löffler A, Furkert J, Krause G, Hermosilla R, Schaefer M, Schülein R, Rosenthal W, Oksche A. Wüller S, et al. Among authors: oksche a. J Biol Chem. 2004 Nov 5;279(45):47254-63. doi: 10.1074/jbc.M408154200. Epub 2004 Aug 19. J Biol Chem. 2004. PMID: 15319430 Free article.
N-terminal proteolysis of the endothelin B receptor abolishes its ability to induce EGF receptor transactivation and contractile protein expression in vascular smooth muscle cells.
Grantcharova E, Reusch HP, Grossmann S, Eichhorst J, Krell HW, Beyermann M, Rosenthal W, Oksche A. Grantcharova E, et al. Among authors: oksche a. Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1288-96. doi: 10.1161/01.ATV.0000220377.51354.30. Epub 2006 Apr 6. Arterioscler Thromb Vasc Biol. 2006. PMID: 16601236
164 results