Stefan E - Search Results

1

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.

Skoumbourdis AP, Leclair CA, Stefan E, Turjanski AG, Maguire W, Titus SA, Huang R, Auld DS, Inglese J, Austin CP, Michnick SW, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: stefan e. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92. doi: 10.1016/j.bmcl.2009.01.057. Epub 2009 Jan 23. Bioorg Med Chem Lett. 2009. PMID: 19464886 Free PMC article.

2

Universal strategies in research and drug discovery based on protein-fragment complementation assays.

Michnick SW, Ear PH, Manderson EN, Remy I, Stefan E. Michnick SW, et al. Among authors: stefan e. Nat Rev Drug Discov. 2007 Jul;6(7):569-82. doi: 10.1038/nrd2311. Nat Rev Drug Discov. 2007. PMID: 17599086 Review.

3

Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo.

Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SW. Stefan E, et al. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16916-21. doi: 10.1073/pnas.0704257104. Epub 2007 Oct 17. Proc Natl Acad Sci U S A. 2007. PMID: 17942691 Free PMC article.

4

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin.

Nyfeler B, Reiterer V, Wendeler MW, Stefan E, Zhang B, Michnick SW, Hauri HP. Nyfeler B, et al. Among authors: stefan e. J Cell Biol. 2008 Feb 25;180(4):705-12. doi: 10.1083/jcb.200709100. Epub 2008 Feb 18. J Cell Biol. 2008. PMID: 18283111 Free PMC article.

5

In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs.

Röck R, Bachmann V, Bhang HE, Malleshaiah M, Raffeiner P, Mayrhofer JE, Tschaikner PM, Bister K, Aanstad P, Pomper MG, Michnick SW, Stefan E. Röck R, et al. Among authors: stefan e. Sci Rep. 2015 Jun 23;5:11133. doi: 10.1038/srep11133. Sci Rep. 2015. PMID: 26099953 Free PMC article.

6

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. Stefan E, et al. Nat Commun. 2011 Dec 20;2:598. doi: 10.1038/ncomms1605. Nat Commun. 2011. PMID: 22186894 Free PMC article.

7

Interplay of PKA and Rac: fine-tuning of Rac localization and signaling.

Bachmann VA, Bister K, Stefan E. Bachmann VA, et al. Among authors: stefan e. Small GTPases. 2013 Oct-Dec;4(4):247-51. doi: 10.4161/sgtp.27281. Epub 2013 Dec 10. Small GTPases. 2013. PMID: 24322054 Free PMC article. Review.

8

Impact of kinase activating and inactivating patient mutations on binary PKA interactions.

Röck R, Mayrhofer JE, Bachmann V, Stefan E. Röck R, et al. Among authors: stefan e. Front Pharmacol. 2015 Aug 18;6:170. doi: 10.3389/fphar.2015.00170. eCollection 2015. Front Pharmacol. 2015. PMID: 26347651 Free PMC article.

9

Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.

Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E. Bachmann VA, et al. Among authors: stefan e. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7786-91. doi: 10.1073/pnas.1608061113. Epub 2016 Jun 28. Proc Natl Acad Sci U S A. 2016. PMID: 27357676 Free PMC article.

10

The many faces of compartmentalized PKA signalosomes.

Torres-Quesada O, Mayrhofer JE, Stefan E. Torres-Quesada O, et al. Among authors: stefan e. Cell Signal. 2017 Sep;37:1-11. doi: 10.1016/j.cellsig.2017.05.012. Epub 2017 May 18. Cell Signal. 2017. PMID: 28528970 Free article. Review.

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