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Page 1
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, D'Amours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, Homer RJ, Cohn L, Huang X, Moran MM, Jordt SE. Caceres AI, et al. Among authors: witek js. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9099-104. doi: 10.1073/pnas.0900591106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458046 Free PMC article.
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM. Just S, et al. PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018. PLoS One. 2018. PMID: 29385160 Free PMC article.
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity.
Kasaian MT, Whitters MJ, Carter LL, Lowe LD, Jussif JM, Deng B, Johnson KA, Witek JS, Senices M, Konz RF, Wurster AL, Donaldson DD, Collins M, Young DA, Grusby MJ. Kasaian MT, et al. Among authors: witek js. Immunity. 2002 Apr;16(4):559-69. doi: 10.1016/s1074-7613(02)00295-9. Immunity. 2002. PMID: 11970879 Free article.