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Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.
Kent D, Ng SS, Syanda AM, Khoshkenar P, Ronzoni R, Li CZ, Zieger M, Greer C, Hatch S, Segal J, Blackford SJI, Im YR, Chowdary V, Ismaili T, Danovi D, Lewis PA, Irving JA, Sahdeo S, Lomas DA, Ebner D, Mueller C, Rashid ST. Kent D, et al. Among authors: blackford sji. Hepatology. 2024 Jul 2. doi: 10.1097/HEP.0000000000000969. Online ahead of print. Hepatology. 2024. PMID: 38954820
Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease.
Jobbins AM, Haberman N, Artigas N, Amourda C, Paterson HAB, Yu S, Blackford SJI, Montoya A, Dore M, Wang YF, Sardini A, Cebola I, Zuber J, Rashid ST, Lenhard B, Vernia S. Jobbins AM, et al. Among authors: blackford sji. Nucleic Acids Res. 2022 Apr 8;50(6):3379-3393. doi: 10.1093/nar/gkac165. Nucleic Acids Res. 2022. PMID: 35293570 Free PMC article.
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency.
Li CZ, Ogawa H, Ng SS, Chen X, Kishimoto E, Sakabe K, Fukami A, Hu YC, Mayhew CN, Hellmann J, Miethke A, Tasnova NL, Blackford SJI, Tang ZM, Syanda AM, Ma L, Xiao F, Sambrotta M, Tavabie O, Soares F, Baker O, Danovi D, Hayashi H, Thompson RJ, Rashid ST, Asai A. Li CZ, et al. Among authors: blackford sji. JHEP Rep. 2022 Feb 1;4(4):100446. doi: 10.1016/j.jhepr.2022.100446. eCollection 2022 Apr. JHEP Rep. 2022. PMID: 35284810 Free PMC article.
58 results