Smith N - Search Results

1

Understanding how diverse beta-mannanases recognize heterogeneous substrates.

Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Tailford LE, et al. Among authors: smith n. Biochemistry. 2009 Jul 28;48(29):7009-18. doi: 10.1021/bi900515d. Biochemistry. 2009. PMID: 19441796

2

Mannose foraging by Bacteroides thetaiotaomicron: structure and specificity of the beta-mannosidase, BtMan2A.

Tailford LE, Money VA, Smith NL, Dumon C, Davies GJ, Gilbert HJ. Tailford LE, et al. J Biol Chem. 2007 Apr 13;282(15):11291-9. doi: 10.1074/jbc.M610964200. Epub 2007 Feb 7. J Biol Chem. 2007. PMID: 17287210 Free article.

3

Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont.

Zhu Y, Suits MD, Thompson AJ, Chavan S, Dinev Z, Dumon C, Smith N, Moremen KW, Xiang Y, Siriwardena A, Williams SJ, Gilbert HJ, Davies GJ. Zhu Y, et al. Among authors: smith n. Nat Chem Biol. 2010 Feb;6(2):125-32. doi: 10.1038/nchembio.278. Epub 2009 Dec 27. Nat Chem Biol. 2010. PMID: 20081828 Free PMC article.

4

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Tailford LE, Offen WA, Smith NL, Dumon C, Morland C, Gratien J, Heck MP, Stick RV, Blériot Y, Vasella A, Gilbert HJ, Davies GJ. Tailford LE, et al. Nat Chem Biol. 2008 May;4(5):306-12. doi: 10.1038/nchembio.81. Nat Chem Biol. 2008. PMID: 18408714

5

Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum.

Taylor EJ, Smith NL, Turkenburg JP, D'Souza S, Gilbert HJ, Davies GJ. Taylor EJ, et al. Biochem J. 2006 Apr 1;395(1):31-7. doi: 10.1042/BJ20051780. Biochem J. 2006. PMID: 16336192 Free PMC article.

6

Substrate distortion by a lichenase highlights the different conformational itineraries harnessed by related glycoside hydrolases.

Money VA, Smith NL, Scaffidi A, Stick RV, Gilbert HJ, Davies GJ. Money VA, et al. Angew Chem Int Ed Engl. 2006 Aug 4;45(31):5136-40. doi: 10.1002/anie.200600802. Angew Chem Int Ed Engl. 2006. PMID: 16823793 No abstract available.

7

Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix.

Smith NL, Taylor EJ, Lindsay AM, Charnock SJ, Turkenburg JP, Dodson EJ, Davies GJ, Black GW. Smith NL, et al. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17652-7. doi: 10.1073/pnas.0504782102. Epub 2005 Nov 28. Proc Natl Acad Sci U S A. 2005. PMID: 16314578 Free PMC article.

8

Evidence for a dual binding mode of dockerin modules to cohesins.

Carvalho AL, Dias FM, Nagy T, Prates JA, Proctor MR, Smith N, Bayer EA, Davies GJ, Ferreira LM, Romão MJ, Fontes CM, Gilbert HJ. Carvalho AL, et al. Among authors: smith n. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3089-94. doi: 10.1073/pnas.0611173104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360613 Free PMC article.

9

Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations.

Elmabrouk ZH, Vincent F, Zhang M, Smith NL, Turkenburg JP, Charnock SJ, Black GW, Taylor EJ. Elmabrouk ZH, et al. Proteins. 2011 Mar;79(3):965-74. doi: 10.1002/prot.22938. Epub 2010 Dec 18. Proteins. 2011. PMID: 21287626

10

The location of the ligand-binding site of carbohydrate-binding modules that have evolved from a common sequence is not conserved.

Czjzek M, Bolam DN, Mosbah A, Allouch J, Fontes CM, Ferreira LM, Bornet O, Zamboni V, Darbon H, Smith NL, Black GW, Henrissat B, Gilbert HJ. Czjzek M, et al. Among authors: smith nl. J Biol Chem. 2001 Dec 21;276(51):48580-7. doi: 10.1074/jbc.M109142200. Epub 2001 Oct 22. J Biol Chem. 2001. PMID: 11673472 Free article.

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