Chu W - Search Results

1

[(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization.

Xu J, Chu W, Tu Z, Jones LA, Luedtke RR, Perlmutter JS, Mintun MA, Mach RH. Xu J, et al. Among authors: chu w. Synapse. 2009 Sep;63(9):717-28. doi: 10.1002/syn.20652. Synapse. 2009. PMID: 19425052 Free PMC article.

2

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

Chu W, Tu Z, McElveen E, Xu J, Taylor M, Luedtke RR, Mach RH. Chu W, et al. Bioorg Med Chem. 2005 Jan 3;13(1):77-87. doi: 10.1016/j.bmc.2004.09.054. Bioorg Med Chem. 2005. PMID: 15582454

3

Synthesis and in vivo evaluation of [11C]PJ34, a potential radiotracer for imaging the role of PARP-1 in necrosis.

Tu Z, Chu W, Zhang J, Dence CS, Welch MJ, Mach RH. Tu Z, et al. Among authors: chu w. Nucl Med Biol. 2005 Jul;32(5):437-43. doi: 10.1016/j.nucmedbio.2005.03.001. Nucl Med Biol. 2005. PMID: 15982573

4

N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.

Chu W, Zhang J, Zeng C, Rothfuss J, Tu Z, Chu Y, Reichert DE, Welch MJ, Mach RH. Chu W, et al. Among authors: chu y. J Med Chem. 2005 Dec 1;48(24):7637-47. doi: 10.1021/jm0506625. J Med Chem. 2005. PMID: 16302804

5

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Among authors: chu w. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

6

Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

Chu W, Rothfuss J, d'Avignon A, Zeng C, Zhou D, Hotchkiss RS, Mach RH. Chu W, et al. J Med Chem. 2007 Jul 26;50(15):3751-5. doi: 10.1021/jm070506t. Epub 2007 Jun 23. J Med Chem. 2007. PMID: 17585855

7

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH. Chu W, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1222-31. doi: 10.1016/j.bmc.2008.12.025. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19119012 Free PMC article.

8

[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98.

Zhou D, Chu W, Chen DL, Wang Q, Reichert DE, Rothfuss J, D'Avignon A, Welch MJ, Mach RH. Zhou D, et al. Among authors: chu w. Org Biomol Chem. 2009 Apr 7;7(7):1337-48. doi: 10.1039/b819024k. Epub 2009 Feb 16. Org Biomol Chem. 2009. PMID: 19300818 Free PMC article.

9

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

Chu W, Rothfuss J, Chu Y, Zhou D, Mach RH. Chu W, et al. Among authors: chu y. J Med Chem. 2009 Apr 23;52(8):2188-91. doi: 10.1021/jm900135r. J Med Chem. 2009. PMID: 19326941

10

Evaluation of D2 and D3 dopamine receptor selective compounds on L-dopa-dependent abnormal involuntary movements in rats.

Kumar R, Riddle LR, Griffin SA, Chu W, Vangveravong S, Neisewander J, Mach RH, Luedtke RR. Kumar R, et al. Among authors: chu w. Neuropharmacology. 2009 May-Jun;56(6-7):956-69. doi: 10.1016/j.neuropharm.2009.01.019. Epub 2009 Feb 5. Neuropharmacology. 2009. PMID: 19371586 Free PMC article.

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