Romo D - Search Results

1

Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A.

Kuznetsov G, Xu Q, Rudolph-Owen L, Tendyke K, Liu J, Towle M, Zhao N, Marsh J, Agoulnik S, Twine N, Parent L, Chen Z, Shie JL, Jiang Y, Zhang H, Du H, Boivin R, Wang Y, Romo D, Littlefield BA. Kuznetsov G, et al. Among authors: romo d. Mol Cancer Ther. 2009 May;8(5):1250-60. doi: 10.1158/1535-7163.MCT-08-1026. Epub 2009 May 5. Mol Cancer Ther. 2009. PMID: 19417157 Free PMC article.

2

Editorial: Strategies for cellular target identification of natural products.

Romo D, Liu JO. Romo D, et al. Nat Prod Rep. 2016 May 4;33(5):592-4. doi: 10.1039/c6np90016j. Nat Prod Rep. 2016. PMID: 27118358 No abstract available.

3

Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.

Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Merrick WC, Romo D, Liu JO. Low WK, et al. Among authors: romo d. Mol Cell. 2005 Dec 9;20(5):709-22. doi: 10.1016/j.molcel.2005.10.008. Mol Cell. 2005. PMID: 16337595 Free article.

4

Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA).

Kommaraju SS, Aulicino J, Gobbooru S, Li J, Zhu M, Romo D, Low WK. Kommaraju SS, et al. Among authors: romo d. Biochem Cell Biol. 2020 Aug;98(4):502-510. doi: 10.1139/bcb-2019-0307. Epub 2020 Feb 2. Biochem Cell Biol. 2020. PMID: 32008367

5

Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative.

Romo D, Choi NS, Li S, Buchler I, Shi Z, Liu JO. Romo D, et al. J Am Chem Soc. 2004 Sep 1;126(34):10582-8. doi: 10.1021/ja040065s. J Am Chem Soc. 2004. PMID: 15327314

6

Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.

Low WK, Li J, Zhu M, Kommaraju SS, Shah-Mittal J, Hull K, Liu JO, Romo D. Low WK, et al. Among authors: romo d. Bioorg Med Chem. 2014 Jan 1;22(1):116-25. doi: 10.1016/j.bmc.2013.11.046. Epub 2013 Dec 4. Bioorg Med Chem. 2014. PMID: 24359706 Free PMC article.

7

Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII.

Dang Y, Low WK, Xu J, Gehring NH, Dietz HC, Romo D, Liu JO. Dang Y, et al. Among authors: romo d. J Biol Chem. 2009 Aug 28;284(35):23613-21. doi: 10.1074/jbc.M109.009985. Epub 2009 Jul 1. J Biol Chem. 2009. PMID: 19570977 Free PMC article.

8

Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A.

Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Rzasa RM, Shea HA, Li S, Park K, Ma G, Romo D, Liu JO. Low WK, et al. Among authors: romo d. Methods Enzymol. 2007;431:303-24. doi: 10.1016/S0076-6879(07)31014-8. Methods Enzymol. 2007. PMID: 17923240 Review.

9

Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.

Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO. Dang Y, et al. Among authors: romo d. J Biol Chem. 2006 Oct 27;281(43):32870-8. doi: 10.1074/jbc.M606149200. Epub 2006 Sep 2. J Biol Chem. 2006. PMID: 16951406 Free article.

10

Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.

Naineni SK, Liang J, Hull K, Cencic R, Zhu M, Northcote P, Teesdale-Spittle P, Romo D, Nagar B, Pelletier J. Naineni SK, et al. Among authors: romo d. Cell Chem Biol. 2021 Jun 17;28(6):825-834.e6. doi: 10.1016/j.chembiol.2020.12.006. Epub 2021 Jan 6. Cell Chem Biol. 2021. PMID: 33412110 Free PMC article.

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