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MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis.
Antoniades C, Shirodaria C, Leeson P, Baarholm OA, Van-Assche T, Cunnington C, Pillai R, Ratnatunga C, Tousoulis D, Stefanadis C, Refsum H, Channon KM. Antoniades C, et al. Circulation. 2009 May 12;119(18):2507-15. doi: 10.1161/CIRCULATIONAHA.108.808675. Epub 2009 Apr 27. Circulation. 2009. PMID: 19398669
GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.
Antoniades C, Shirodaria C, Van Assche T, Cunnington C, Tegeder I, Lötsch J, Guzik TJ, Leeson P, Diesch J, Tousoulis D, Stefanadis C, Costigan M, Woolf CJ, Alp NJ, Channon KM. Antoniades C, et al. J Am Coll Cardiol. 2008 Jul 8;52(2):158-65. doi: 10.1016/j.jacc.2007.12.062. J Am Coll Cardiol. 2008. PMID: 18598896 Free PMC article.
Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis.
Antoniades C, Shirodaria C, Leeson P, Antonopoulos A, Warrick N, Van-Assche T, Cunnington C, Tousoulis D, Pillai R, Ratnatunga C, Stefanadis C, Channon KM. Antoniades C, et al. Eur Heart J. 2009 May;30(9):1142-50. doi: 10.1093/eurheartj/ehp061. Epub 2009 Mar 18. Eur Heart J. 2009. PMID: 19297385
Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease.
Cunnington C, Van Assche T, Shirodaria C, Kylintireas I, Lindsay AC, Lee JM, Antoniades C, Margaritis M, Lee R, Cerrato R, Crabtree MJ, Francis JM, Sayeed R, Ratnatunga C, Pillai R, Choudhury RP, Neubauer S, Channon KM. Cunnington C, et al. Circulation. 2012 Mar 20;125(11):1356-66. doi: 10.1161/CIRCULATIONAHA.111.038919. Epub 2012 Feb 7. Circulation. 2012. PMID: 22315282 Free PMC article. Clinical Trial.
Gene therapy targeting inflammation in atherosclerosis.
Van-Assche T, Huygelen V, Crabtree MJ, Antoniades C. Van-Assche T, et al. Curr Pharm Des. 2011 Dec;17(37):4210-23. doi: 10.2174/138161211798764799. Curr Pharm Des. 2011. PMID: 22204379 Review.
38 results