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Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture.
Cassol OJ Jr, Comim CM, Silva BR, Hermani FV, Constantino LS, Felisberto F, Petronilho F, Hallak JE, De Martinis BS, Zuardi AW, Crippa JA, Quevedo J, Dal-Pizzol F. Cassol OJ Jr, et al. Among authors: hermani fv. Brain Res. 2010 Aug 12;1348:128-38. doi: 10.1016/j.brainres.2010.06.023. Epub 2010 Jun 16. Brain Res. 2010. PMID: 20561509
Cognitive dysfunction is sustained after rescue therapy in experimental cerebral malaria, and is reduced by additive antioxidant therapy.
Reis PA, Comim CM, Hermani F, Silva B, Barichello T, Portella AC, Gomes FC, Sab IM, Frutuoso VS, Oliveira MF, Bozza PT, Bozza FA, Dal-Pizzol F, Zimmerman GA, Quevedo J, Castro-Faria-Neto HC. Reis PA, et al. PLoS Pathog. 2010 Jun 24;6(6):e1000963. doi: 10.1371/journal.ppat.1000963. PLoS Pathog. 2010. PMID: 20585569 Free PMC article.