Shi Q - Search Results

1

Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis.

Shi Q, Risa Ø, Sonnewald U, Gibson GE. Shi Q, et al. J Neurochem. 2009 May;109 Suppl 1(Suppl 1):214-21. doi: 10.1111/j.1471-4159.2009.05955.x. J Neurochem. 2009. PMID: 19393030 Free PMC article.

2

Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.

Shi Q, Chen HL, Xu H, Gibson GE. Shi Q, et al. J Biol Chem. 2005 Mar 25;280(12):10888-96. doi: 10.1074/jbc.M409064200. Epub 2005 Jan 12. J Biol Chem. 2005. PMID: 15649899 Free article.

3

Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.

Shi Q, Xu H, Kleinman WA, Gibson GE. Shi Q, et al. Biochim Biophys Acta. 2008 Apr;1782(4):229-38. doi: 10.1016/j.bbadis.2007.12.008. Epub 2007 Dec 31. Biochim Biophys Acta. 2008. PMID: 18206986 Free PMC article.

4

Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex.

Shi Q, Xu H, Yu H, Zhang N, Ye Y, Estevez AG, Deng H, Gibson GE. Shi Q, et al. J Biol Chem. 2011 May 20;286(20):17640-8. doi: 10.1074/jbc.M110.203018. Epub 2011 Mar 25. J Biol Chem. 2011. PMID: 21454586 Free PMC article.

5

Up-regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR-743a.

Shi Q, Gibson GE. Shi Q, et al. J Neurochem. 2011 Aug;118(3):440-8. doi: 10.1111/j.1471-4159.2011.07333.x. Epub 2011 Jun 24. J Neurochem. 2011. PMID: 21623795 Free PMC article.

6

Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.

Gibson GE, Chen HL, Xu H, Qiu L, Xu Z, Denton TT, Shi Q. Gibson GE, et al. Among authors: shi q. Neurobiol Aging. 2012 Jun;33(6):1121.e13-24. doi: 10.1016/j.neurobiolaging.2011.11.003. Epub 2011 Dec 14. Neurobiol Aging. 2012. PMID: 22169199 Free PMC article.

7

Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability.

Shi Q, Karuppagounder SS, Xu H, Pechman D, Chen H, Gibson GE. Shi Q, et al. Neurochem Int. 2007 Jun;50(7-8):921-31. doi: 10.1016/j.neuint.2007.03.010. Epub 2007 Apr 7. Neurochem Int. 2007. PMID: 17482317 Free PMC article.

8

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism.

Karuppagounder SS, Shi Q, Xu H, Gibson GE. Karuppagounder SS, et al. Among authors: shi q. Neurobiol Dis. 2007 May;26(2):353-62. doi: 10.1016/j.nbd.2007.01.011. Epub 2007 Feb 8. Neurobiol Dis. 2007. PMID: 17398105 Free PMC article.

9

Oxidative stress and transcriptional regulation in Alzheimer disease.

Shi Q, Gibson GE. Shi Q, et al. Alzheimer Dis Assoc Disord. 2007 Oct-Dec;21(4):276-91. doi: 10.1097/WAD.0b013e31815721c3. Alzheimer Dis Assoc Disord. 2007. PMID: 18090434 Free PMC article. Review.

10

Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimer's disease.

Gibson GE, Karuppagounder SS, Shi Q. Gibson GE, et al. Among authors: shi q. Ann N Y Acad Sci. 2008 Dec;1147:221-32. doi: 10.1196/annals.1427.038. Ann N Y Acad Sci. 2008. PMID: 19076444 Free PMC article. Review.

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