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Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis.
Zhu L, Stalker TJ, Fong KP, Jiang H, Tran A, Crichton I, Lee EK, Neeves KB, Maloney SF, Kikutani H, Kumanogoh A, Pure E, Diamond SL, Brass LF. Zhu L, et al. Among authors: jiang h. Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1039-45. doi: 10.1161/ATVBAHA.109.185405. Epub 2009 Apr 23. Arterioscler Thromb Vasc Biol. 2009. PMID: 19390055 Free PMC article.
Contact-dependent signaling events that promote thrombus formation.
Brass LF, Jiang H, Wu J, Stalker TJ, Zhu L. Brass LF, et al. Among authors: jiang h. Blood Cells Mol Dis. 2006 Mar-Apr;36(2):157-61. doi: 10.1016/j.bcmd.2005.12.015. Epub 2006 Feb 13. Blood Cells Mol Dis. 2006. PMID: 16473534 Review.
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
Zhu L, Bergmeier W, Wu J, Jiang H, Stalker TJ, Cieslak M, Fan R, Boumsell L, Kumanogoh A, Kikutani H, Tamagnone L, Wagner DD, Milla ME, Brass LF. Zhu L, et al. Among authors: jiang h. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1621-6. doi: 10.1073/pnas.0606344104. Epub 2007 Jan 23. Proc Natl Acad Sci U S A. 2007. PMID: 17244710 Free PMC article.
Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.
Wannemacher KM, Zhu L, Jiang H, Fong KP, Stalker TJ, Lee D, Tran AN, Neeves KB, Maloney S, Kumanogoh A, Kikutani H, Hammer DA, Diamond SL, Brass LF. Wannemacher KM, et al. Among authors: jiang h. Blood. 2010 Dec 16;116(25):5707-15. doi: 10.1182/blood-2010-04-279943. Epub 2010 Sep 20. Blood. 2010. PMID: 20855865 Free PMC article.
Activation of Rap1B by G(i) family members in platelets.
Woulfe D, Jiang H, Mortensen R, Yang J, Brass LF. Woulfe D, et al. Among authors: jiang h. J Biol Chem. 2002 Jun 28;277(26):23382-90. doi: 10.1074/jbc.M202212200. Epub 2002 Apr 22. J Biol Chem. 2002. PMID: 11970953 Free article.
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