Giordano FA - Search Results

1

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis.

Appelt JU, Giordano FA, Ecker M, Roeder I, Grund N, Hotz-Wagenblatt A, Opelz G, Zeller WJ, Allgayer H, Fruehauf S, Laufs S. Appelt JU, et al. Among authors: giordano fa. Gene Ther. 2009 Jul;16(7):885-93. doi: 10.1038/gt.2009.37. Epub 2009 Apr 23. Gene Ther. 2009. PMID: 19387483

2

Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns.

Laufs S, Nagy KZ, Giordano FA, Hotz-Wagenblatt A, Zeller WJ, Fruehauf S. Laufs S, et al. Among authors: giordano fa. Mol Ther. 2004 Nov;10(5):874-81. doi: 10.1016/j.ymthe.2004.08.001. Mol Ther. 2004. PMID: 15509505 Free article.

3

Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.

Giordano FA, Fehse B, Hotz-Wagenblatt A, Jonnakuty S, del Val C, Appelt JU, Nagy KZ, Kuehlcke K, Naundorf S, Zander AR, Zeller WJ, Ho AD, Fruehauf S, Laufs S. Giordano FA, et al. Bone Marrow Transplant. 2006 Aug;38(3):229-35. doi: 10.1038/sj.bmt.1705424. Epub 2006 Jun 19. Bone Marrow Transplant. 2006. PMID: 16785865

4

New bioinformatic strategies to rapidly characterize retroviral integration sites of gene therapy vectors.

Giordano FA, Hotz-Wagenblatt A, Lauterborn D, Appelt JU, Fellenberg K, Nagy KZ, Zeller WJ, Suhai S, Fruehauf S, Laufs S. Giordano FA, et al. Methods Inf Med. 2007;46(5):542-7. Methods Inf Med. 2007. PMID: 17938776

5

Cold spots in hot spots: transcription start sites of active genes are spared from HIV vector integration.

Giordano FA, Appelt JU, Zucknick M, Abba M, Zeller WJ, Fruehauf S, Allgayer H, Laufs S. Giordano FA, et al. AIDS. 2009 Nov 27;23(18):2535-7. doi: 10.1097/QAD.0b013e3283336432. AIDS. 2009. PMID: 19841571

6

Analysis of self-inactivating lentiviral vector integration sites and flanking gene expression in human peripheral blood progenitor cells after alkylator chemotherapy.

Grund N, Maier P, Giordano FA, Appelt JU, Zucknick M, Li L, Wenz F, Zeller WJ, Fruehauf S, Allgayer H, Laufs S. Grund N, et al. Among authors: giordano fa. Hum Gene Ther. 2010 Aug;21(8):943-56. doi: 10.1089/hum.2009.116. Hum Gene Ther. 2010. PMID: 20210626

7

Unrestricted somatic stem cells: interaction with CD34+ cells in vitro and in vivo, expression of homing genes and exclusion of tumorigenic potential.

Jeltsch KS, Radke TF, Laufs S, Giordano FA, Allgayer H, Wenz F, Zeller WJ, Kögler G, Fruehauf S, Maier P. Jeltsch KS, et al. Among authors: giordano fa. Cytotherapy. 2011 Mar;13(3):357-65. doi: 10.3109/14653249.2010.523076. Epub 2010 Oct 18. Cytotherapy. 2011. PMID: 20950214

8

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy.

Giordano FA, Sorg UR, Appelt JU, Lachmann N, Bleier S, Roeder I, Kleff V, Flasshove M, Zeller WJ, Allgayer H, von Kalle C, Fruehauf S, Moritz T, Laufs S. Giordano FA, et al. Hum Gene Ther. 2011 Jun;22(6):697-710. doi: 10.1089/hum.2010.088. Epub 2011 Apr 11. Hum Gene Ther. 2011. PMID: 21319998

9

A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.

Heckmann D, Laufs S, Maier P, Zucknick M, Giordano FA, Veldwijk MR, Eckstein V, Wenz F, Zeller WJ, Fruehauf S, Allgayer H. Heckmann D, et al. Among authors: giordano fa. Onkologie. 2011;34(10):502-8. doi: 10.1159/000332390. Epub 2011 Sep 20. Onkologie. 2011. PMID: 21985848

10

Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors.

Kymäläinen H, Appelt JU, Giordano FA, Davies AF, Ogilvie CM, Ahmed SG, Laufs S, Schmidt M, Bode J, Yáñez-Muñoz RJ, Dickson G. Kymäläinen H, et al. Among authors: giordano fa. Hum Gene Ther. 2014 May;25(5):428-42. doi: 10.1089/hum.2013.172. Epub 2014 Apr 10. Hum Gene Ther. 2014. PMID: 24483952 Free PMC article.

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