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Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Marco-Contelles J, León R, de los Ríos C, Samadi A, Bartolini M, Andrisano V, Huertas O, Barril X, Luque FJ, Rodríguez-Franco MI, López B, López MG, García AG, Carreiras Mdo C, Villarroya M. Marco-Contelles J, et al. Among authors: barril x. J Med Chem. 2009 May 14;52(9):2724-32. doi: 10.1021/jm801292b. J Med Chem. 2009. PMID: 19374444
Fractional description of free energies of solvation.
Luque FJ, Barril X, Orozco M. Luque FJ, et al. Among authors: barril x. J Comput Aided Mol Des. 1999 Mar;13(2):139-52. doi: 10.1023/a:1008036526741. J Comput Aided Mol Des. 1999. PMID: 10091120
Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. Among authors: barril x. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010
91 results