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Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
Jacobs B, De Roock W, Piessevaux H, Van Oirbeek R, Biesmans B, De Schutter J, Fieuws S, Vandesompele J, Peeters M, Van Laethem JL, Humblet Y, Pénault-Llorca F, De Hertogh G, Laurent-Puig P, Van Cutsem E, Tejpar S. Jacobs B, et al. J Clin Oncol. 2009 Oct 20;27(30):5068-74. doi: 10.1200/JCO.2008.21.3744. Epub 2009 Sep 8. J Clin Oncol. 2009. PMID: 19738126
A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy.
Saridaki Z, Weidhaas JB, Lenz HJ, Laurent-Puig P, Jacobs B, De Schutter J, De Roock W, Salzman DW, Zhang W, Yang D, Pilati C, Bouché O, Piessevaux H, Tejpar S. Saridaki Z, et al. Among authors: jacobs b. Clin Cancer Res. 2014 Sep 1;20(17):4499-4510. doi: 10.1158/1078-0432.CCR-14-0348. Clin Cancer Res. 2014. PMID: 25183481 Free PMC article.
EGFR-targeted therapy.
Vecchione L, Jacobs B, Normanno N, Ciardiello F, Tejpar S. Vecchione L, et al. Among authors: jacobs b. Exp Cell Res. 2011 Nov 15;317(19):2765-71. doi: 10.1016/j.yexcr.2011.08.021. Epub 2011 Sep 7. Exp Cell Res. 2011. PMID: 21925171 Review.
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells.
Bosch-Vilaró A, Jacobs B, Pomella V, Abbasi Asbagh L, Kirkland R, Michel J, Singh S, Liu X, Kim P, Weitsman G, Barber PR, Vojnovic B, Ng T, Tejpar S. Bosch-Vilaró A, et al. Among authors: jacobs b. Oncotarget. 2017 Jan 17;8(3):4277-4288. doi: 10.18632/oncotarget.13834. Oncotarget. 2017. PMID: 28032592 Free PMC article.
Clinical and molecular characteristics and treatment outcomes of advanced right-colon, left-colon and rectal cancers: data from 1180 patients in a phase III trial of panitumumab with an extended biomarker panel.
Seligmann JF, Elliott F, Richman S, Hemmings G, Brown S, Jacobs B, Williams C, Tejpar S, Barrett JH, Quirke P, Seymour M. Seligmann JF, et al. Among authors: jacobs b. Ann Oncol. 2020 Aug;31(8):1021-1029. doi: 10.1016/j.annonc.2020.04.476. Epub 2020 May 6. Ann Oncol. 2020. PMID: 32387453 Free article. Clinical Trial.
KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy.
Valtorta E, Misale S, Sartore-Bianchi A, Nagtegaal ID, Paraf F, Lauricella C, Dimartino V, Hobor S, Jacobs B, Ercolani C, Lamba S, Scala E, Veronese S, Laurent-Puig P, Siena S, Tejpar S, Mottolese M, Punt CJ, Gambacorta M, Bardelli A, Di Nicolantonio F. Valtorta E, et al. Among authors: jacobs b. Int J Cancer. 2013 Sep 1;133(5):1259-65. doi: 10.1002/ijc.28106. Epub 2013 Mar 16. Int J Cancer. 2013. PMID: 23404247 Free article.
1,862 results