Giorgio M - Search Results

1

The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury.

Carpi A, Menabò R, Kaludercic N, Pelicci P, Di Lisa F, Giorgio M. Carpi A, et al. Among authors: giorgio m. Biochim Biophys Acta. 2009 Jul;1787(7):774-80. doi: 10.1016/j.bbabio.2009.04.001. Epub 2009 Apr 9. Biochim Biophys Acta. 2009. PMID: 19362067 Free article.

2

A family of Shc related proteins with conserved PTB, CH1 and SH2 regions.

Pelicci G, Dente L, De Giuseppe A, Verducci-Galletti B, Giuli S, Mele S, Vetriani C, Giorgio M, Pandolfi PP, Cesareni G, Pelicci PG. Pelicci G, et al. Among authors: giorgio m. Oncogene. 1996 Aug 1;13(3):633-41. Oncogene. 1996. PMID: 8760305

3

The p66shc adaptor protein controls oxidative stress response and life span in mammals.

Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG. Migliaccio E, et al. Among authors: giorgio m. Nature. 1999 Nov 18;402(6759):309-13. doi: 10.1038/46311. Nature. 1999. PMID: 10580504

4

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

Trinei M, Giorgio M, Cicalese A, Barozzi S, Ventura A, Migliaccio E, Milia E, Padura IM, Raker VA, Maccarana M, Petronilli V, Minucci S, Bernardi P, Lanfrancone L, Pelicci PG. Trinei M, et al. Among authors: giorgio m. Oncogene. 2002 May 30;21(24):3872-8. doi: 10.1038/sj.onc.1205513. Oncogene. 2002. PMID: 12032825

5

Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

Napoli C, Martin-Padura I, de Nigris F, Giorgio M, Mansueto G, Somma P, Condorelli M, Sica G, De Rosa G, Pelicci P. Napoli C, et al. Among authors: giorgio m. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2112-6. doi: 10.1073/pnas.0336359100. Epub 2003 Feb 5. Proc Natl Acad Sci U S A. 2003. PMID: 12571362 Free PMC article.

6

Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis.

Giorgio M, Migliaccio E, Orsini F, Paolucci D, Moroni M, Contursi C, Pelliccia G, Luzi L, Minucci S, Marcaccio M, Pinton P, Rizzuto R, Bernardi P, Paolucci F, Pelicci PG. Giorgio M, et al. Cell. 2005 Jul 29;122(2):221-33. doi: 10.1016/j.cell.2005.05.011. Cell. 2005. PMID: 16051147 Free article.

7

Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress.

Menini S, Amadio L, Oddi G, Ricci C, Pesce C, Pugliese F, Giorgio M, Migliaccio E, Pelicci P, Iacobini C, Pugliese G. Menini S, et al. Among authors: giorgio m. Diabetes. 2006 Jun;55(6):1642-50. doi: 10.2337/db05-1477. Diabetes. 2006. PMID: 16731826

8

p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis.

Pellegrini M, Finetti F, Petronilli V, Ulivieri C, Giusti F, Lupetti P, Giorgio M, Pelicci PG, Bernardi P, Baldari CT. Pellegrini M, et al. Among authors: giorgio m. Cell Death Differ. 2007 Feb;14(2):338-47. doi: 10.1038/sj.cdd.4401997. Epub 2006 Jun 23. Cell Death Differ. 2007. PMID: 16794602

9

Mitochondrial DNA copy number is regulated by cellular proliferation: a role for Ras and p66(Shc).

Trinei M, Berniakovich I, Pelicci PG, Giorgio M. Trinei M, et al. Among authors: giorgio m. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):624-30. doi: 10.1016/j.bbabio.2006.05.029. Epub 2006 May 25. Biochim Biophys Acta. 2006. PMID: 16829231 Free article.

10

Regulatory effects of the mitochondrial energetic status on mitochondrial p66Shc.

Orsini F, Moroni M, Contursi C, Yano M, Pelicci P, Giorgio M, Migliaccio E. Orsini F, et al. Among authors: giorgio m. Biol Chem. 2006 Oct-Nov;387(10-11):1405-10. doi: 10.1515/BC.2006.176. Biol Chem. 2006. PMID: 17081113

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