Gardner KH - Search Results

1

Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).

Partch CL, Card PB, Amezcua CA, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Biol Chem. 2009 May 29;284(22):15184-92. doi: 10.1074/jbc.M808479200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324882 Free PMC article.

2

Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.

Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH. Erbel PJ, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15504-9. doi: 10.1073/pnas.2533374100. Epub 2003 Dec 10. Proc Natl Acad Sci U S A. 2003. PMID: 14668441 Free PMC article.

3

Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.

Card PB, Erbel PJ, Gardner KH. Card PB, et al. Among authors: gardner kh. J Mol Biol. 2005 Oct 28;353(3):664-77. doi: 10.1016/j.jmb.2005.08.043. Epub 2005 Sep 6. J Mol Biol. 2005. PMID: 16181639

4

Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.

Mukherjee S, Partch CL, Lehotzky RE, Whitham CV, Chu H, Bevins CL, Gardner KH, Hooper LV. Mukherjee S, et al. Among authors: gardner kh. J Biol Chem. 2009 Feb 20;284(8):4881-8. doi: 10.1074/jbc.M808077200. Epub 2008 Dec 18. J Biol Chem. 2009. PMID: 19095652 Free PMC article.

5

ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

Evans MR, Card PB, Gardner KH. Evans MR, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2617-22. doi: 10.1073/pnas.0808270106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196990 Free PMC article.

6

Coactivator recruitment: a new role for PAS domains in transcriptional regulation by the bHLH-PAS family.

Partch CL, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Cell Physiol. 2010 Jun;223(3):553-7. doi: 10.1002/jcp.22067. J Cell Physiol. 2010. PMID: 20112293 Free PMC article. Review.

7

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.

Partch CL, Gardner KH. Partch CL, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7739-44. doi: 10.1073/pnas.1101357108. Epub 2011 Apr 21. Proc Natl Acad Sci U S A. 2011. PMID: 21512126 Free PMC article.

8

Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.

Guo Y, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH. Guo Y, et al. Among authors: gardner kh. ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26. ACS Chem Biol. 2013. PMID: 23240775 Free PMC article.

9

Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.

Guo Y, Scheuermann TH, Partch CL, Tomchick DR, Gardner KH. Guo Y, et al. Among authors: gardner kh. J Biol Chem. 2015 Mar 20;290(12):7707-21. doi: 10.1074/jbc.M114.632786. Epub 2015 Jan 27. J Biol Chem. 2015. PMID: 25627682 Free PMC article.

10

Identification and optimization of protein domains for NMR studies.

Card PB, Gardner KH. Card PB, et al. Among authors: gardner kh. Methods Enzymol. 2005;394:3-16. doi: 10.1016/S0076-6879(05)94001-9. Methods Enzymol. 2005. PMID: 15808215

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