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Page 1
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.
Uderhardt S, Diarra D, Katzenbeisser J, David JP, Zwerina J, Richards W, Kronke G, Schett G. Uderhardt S, et al. Among authors: richards w. Ann Rheum Dis. 2010 Mar;69(3):592-7. doi: 10.1136/ard.2008.102046. Epub 2009 Mar 19. Ann Rheum Dis. 2010. PMID: 19304568
Dickkopf-1 is a master regulator of joint remodeling.
Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G. Diarra D, et al. Nat Med. 2007 Feb;13(2):156-63. doi: 10.1038/nm1538. Epub 2007 Jan 21. Nat Med. 2007. PMID: 17237793
Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury.
Li X, Grisanti M, Fan W, Asuncion FJ, Tan HL, Dwyer D, Han CY, Yu L, Lee J, Lee E, Barrero M, Kurimoto P, Niu QT, Geng Z, Winters A, Horan T, Steavenson S, Jacobsen F, Chen Q, Haldankar R, Lavallee J, Tipton B, Daris M, Sheng J, Lu HS, Daris K, Deshpande R, Valente EG, Salimi-Moosavi H, Kostenuik PJ, Li J, Liu M, Li C, Lacey DL, Simonet WS, Ke HZ, Babij P, Stolina M, Ominsky MS, Richards WG. Li X, et al. Among authors: richards wg. J Bone Miner Res. 2011 Nov;26(11):2610-21. doi: 10.1002/jbmr.472. J Bone Miner Res. 2011. PMID: 21773994 Free article.
Asthma, allergies, and school.
Richards W. Richards W. Pediatr Ann. 1992 Sep;21(9):575-85. doi: 10.3928/0090-4481-19920901-08. Pediatr Ann. 1992. PMID: 1359499 Review. No abstract available.
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair.
Florio M, Gunasekaran K, Stolina M, Li X, Liu L, Tipton B, Salimi-Moosavi H, Asuncion FJ, Li C, Sun B, Tan HL, Zhang L, Han CY, Case R, Duguay AN, Grisanti M, Stevens J, Pretorius JK, Pacheco E, Jones H, Chen Q, Soriano BD, Wen J, Heron B, Jacobsen FW, Brisan E, Richards WG, Ke HZ, Ominsky MS. Florio M, et al. Among authors: richards wg. Nat Commun. 2016 May 27;7:11505. doi: 10.1038/ncomms11505. Nat Commun. 2016. PMID: 27230681 Free PMC article.
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia.
Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG. Li J, et al. Among authors: richards wg. Bone. 2006 Oct;39(4):754-66. doi: 10.1016/j.bone.2006.03.017. Epub 2006 May 26. Bone. 2006. PMID: 16730481
Etelcalcetide (AMG 416), a peptide agonist of the calcium-sensing receptor, preserved cortical bone structure and bone strength in subtotal nephrectomized rats with established secondary hyperparathyroidism.
Li X, Yu L, Asuncion F, Grisanti M, Alexander S, Hensley K, Han CY, Niu QT, Dwyer D, Villasenor K, Stolina M, Dean C Jr, Ominsky MS, Ke HZ, Tomlinson JE, Richards WG. Li X, et al. Bone. 2017 Dec;105:163-172. doi: 10.1016/j.bone.2017.08.026. Epub 2017 Sep 1. Bone. 2017. PMID: 28867373 Free article.
1,004 results