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Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease.
Giampà C, Middei S, Patassini S, Borreca A, Marullo F, Laurenti D, Bernardi G, Ammassari-Teule M, Fusco FR. Giampà C, et al. Among authors: borreca a. Eur J Neurosci. 2009 Mar;29(5):902-10. doi: 10.1111/j.1460-9568.2009.06649.x. Eur J Neurosci. 2009. PMID: 19291221
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.
Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D'Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G. Corsetti V, et al. Among authors: borreca a. Hum Mol Genet. 2015 Jun 1;24(11):3058-81. doi: 10.1093/hmg/ddv059. Epub 2015 Feb 15. Hum Mol Genet. 2015. PMID: 25687137 Free article.
SMN affects membrane remodelling and anchoring of the protein synthesis machinery.
Gabanella F, Pisani C, Borreca A, Farioli-Vecchioli S, Ciotti MT, Ingegnere T, Onori A, Ammassari-Teule M, Corbi N, Canu N, Monaco L, Passananti C, Di Certo MG. Gabanella F, et al. Among authors: borreca a. J Cell Sci. 2016 Feb 15;129(4):804-16. doi: 10.1242/jcs.176750. Epub 2016 Jan 7. J Cell Sci. 2016. PMID: 26743087
36 results