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BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.
Estupiñán HY, Wang Q, Berglöf A, Schaafsma GCP, Shi Y, Zhou L, Mohammad DK, Yu L, Vihinen M, Zain R, Smith CIE. Estupiñán HY, et al. Among authors: yu l. Leukemia. 2021 May;35(5):1317-1329. doi: 10.1038/s41375-021-01123-6. Epub 2021 Feb 1. Leukemia. 2021. PMID: 33526860 Free PMC article.
Tec family kinases.
Yu L, Smith CI. Yu L, et al. FEBS J. 2011 Jun;278(12):1969. doi: 10.1111/j.1742-4658.2011.08135.x. Epub 2011 May 18. FEBS J. 2011. PMID: 21518256 Free article.
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