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A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.
Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjaer N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, Wenska M, Srivastava P, Zhou C, Honcharenko D, Hess S, Müller E, Bobkov GV, Mikhailov SN, Fava E, Meyer TF, Chattopadhyaya J, Zerial M, Engels JW, Herdewijn P, Wengel J, Kjems J. Bramsen JB, et al. Among authors: bobkov gv. Nucleic Acids Res. 2009 May;37(9):2867-81. doi: 10.1093/nar/gkp106. Epub 2009 Mar 12. Nucleic Acids Res. 2009. PMID: 19282453 Free PMC article.
Synthesis of 2'-O-beta-d-Ribofuranosylnucleosides.
Mikhailov SN, Efimtseva EV, Rodionov AA, Bobkov GV, Kulikova IV, Herdewijn P. Mikhailov SN, et al. Among authors: bobkov gv. Curr Protoc Nucleic Acid Chem. 2007 Jan;Chapter 1:Unit 1.14. doi: 10.1002/0471142700.nc0114s27. Curr Protoc Nucleic Acid Chem. 2007. PMID: 18428962
Detection of RNA hybridization by pyrene-labeled probes.
Wang G, Bobkov GV, Mikhailov SN, Schepers G, Van Aerschot A, Rozenski J, Van der Auweraer M, Herdewijn P, De Feyter S. Wang G, et al. Among authors: bobkov gv. Chembiochem. 2009 May 4;10(7):1175-85. doi: 10.1002/cbic.200900031. Chembiochem. 2009. PMID: 19373795