Nukina N - Search Results

1

Inhibition of Rho kinases enhances the degradation of mutant huntingtin.

Bauer PO, Wong HK, Oyama F, Goswami A, Okuno M, Kino Y, Miyazaki H, Nukina N. Bauer PO, et al. Among authors: nukina n. J Biol Chem. 2009 May 8;284(19):13153-64. doi: 10.1074/jbc.M809229200. Epub 2009 Mar 11. J Biol Chem. 2009. PMID: 19278999 Free PMC article.

2

Gem GTPase and tau: morphological changes induced by gem GTPase in cho cells are antagonized by tau.

Oyama F, Kotliarova S, Harada A, Ito M, Miyazaki H, Ueyama Y, Hirokawa N, Nukina N, Ihara Y. Oyama F, et al. Among authors: nukina n. J Biol Chem. 2004 Jun 25;279(26):27272-7. doi: 10.1074/jbc.M401634200. Epub 2004 Apr 15. J Biol Chem. 2004. PMID: 15087445 Free article.

3

RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells.

Doi H, Okamura K, Bauer PO, Furukawa Y, Shimizu H, Kurosawa M, Machida Y, Miyazaki H, Mitsui K, Kuroiwa Y, Nukina N. Doi H, et al. Among authors: nukina n. J Biol Chem. 2008 Mar 7;283(10):6489-500. doi: 10.1074/jbc.M705306200. Epub 2007 Dec 31. J Biol Chem. 2008. PMID: 18167354 Free article.

4

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, Nukina N. Yamanaka T, et al. Among authors: nukina n. EMBO J. 2008 Mar 19;27(6):827-39. doi: 10.1038/emboj.2008.23. Epub 2008 Feb 21. EMBO J. 2008. PMID: 18288205 Free PMC article.

5

Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy.

Bauer PO, Nukina N. Bauer PO, et al. Among authors: nukina n. Autophagy. 2009 Jul;5(5):747-8. doi: 10.4161/auto.5.5.8704. Epub 2009 Jul 9. Autophagy. 2009. PMID: 19411823

6

The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies.

Bauer PO, Nukina N. Bauer PO, et al. Among authors: nukina n. J Neurochem. 2009 Sep;110(6):1737-65. doi: 10.1111/j.1471-4159.2009.06302.x. Epub 2009 Jul 23. J Neurochem. 2009. PMID: 19650870 Free article. Review.

7

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein.

Bauer PO, Goswami A, Wong HK, Okuno M, Kurosawa M, Yamada M, Miyazaki H, Matsumoto G, Kino Y, Nagai Y, Nukina N. Bauer PO, et al. Among authors: nukina n. Nat Biotechnol. 2010 Mar;28(3):256-63. doi: 10.1038/nbt.1608. Epub 2010 Feb 28. Nat Biotechnol. 2010. PMID: 20190739

8

Genetic ablation and chemical inhibition of IP3R1 reduce mutant huntingtin aggregation.

Bauer PO, Hudec R, Ozaki S, Okuno M, Ebisui E, Mikoshiba K, Nukina N. Bauer PO, et al. Among authors: nukina n. Biochem Biophys Res Commun. 2011 Dec 9;416(1-2):13-7. doi: 10.1016/j.bbrc.2011.10.096. Epub 2011 Oct 28. Biochem Biophys Res Commun. 2011. PMID: 22056561

9

ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT.

Bauer PO, Hudec R, Goswami A, Kurosawa M, Matsumoto G, Mikoshiba K, Nukina N. Bauer PO, et al. Among authors: nukina n. Mol Neurodegener. 2012 Aug 28;7:43. doi: 10.1186/1750-1326-7-43. Mol Neurodegener. 2012. PMID: 22929228 Free PMC article.

10

Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.

Yamanaka T, Wong HK, Tosaki A, Bauer PO, Wada K, Kurosawa M, Shimogori T, Hattori N, Nukina N. Yamanaka T, et al. Among authors: nukina n. PLoS One. 2014 Apr 4;9(4):e93891. doi: 10.1371/journal.pone.0093891. eCollection 2014. PLoS One. 2014. PMID: 24705917 Free PMC article.

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