Horne WC - Search Results

1

Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.

Nakajima A, Sanjay A, Chiusaroli R, Adapala NS, Neff L, Itzsteink C, Horne WC, Baron R. Nakajima A, et al. Among authors: horne wc. J Bone Miner Res. 2009 Jul;24(7):1162-72. doi: 10.1359/jbmr.090205. J Bone Miner Res. 2009. PMID: 19257814 Free PMC article.

2

Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones.

Chiusaroli R, Sanjay A, Henriksen K, Engsig MT, Horne WC, Gu H, Baron R. Chiusaroli R, et al. Among authors: horne wc. Dev Biol. 2003 Sep 15;261(2):537-47. doi: 10.1016/s0012-1606(03)00299-9. Dev Biol. 2003. PMID: 14499658 Free article.

3

Src kinase activity is essential for osteoclast function.

Miyazaki T, Sanjay A, Neff L, Tanaka S, Horne WC, Baron R. Miyazaki T, et al. Among authors: horne wc. J Biol Chem. 2004 Apr 23;279(17):17660-6. doi: 10.1074/jbc.M311032200. Epub 2004 Jan 22. J Biol Chem. 2004. PMID: 14739300 Free article.

4

Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.

Bruzzaniti A, Neff L, Sanjay A, Horne WC, De Camilli P, Baron R. Bruzzaniti A, et al. Among authors: horne wc. Mol Biol Cell. 2005 Jul;16(7):3301-13. doi: 10.1091/mbc.e04-12-1117. Epub 2005 May 4. Mol Biol Cell. 2005. PMID: 15872089 Free PMC article.

5

The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function.

Horne WC, Sanjay A, Bruzzaniti A, Baron R. Horne WC, et al. Immunol Rev. 2005 Dec;208:106-25. doi: 10.1111/j.0105-2896.2005.00335.x. Immunol Rev. 2005. PMID: 16313344 Review.

6

Calpain is required for normal osteoclast function and is down-regulated by calcitonin.

Marzia M, Chiusaroli R, Neff L, Kim NY, Chishti AH, Baron R, Horne WC. Marzia M, et al. Among authors: horne wc. J Biol Chem. 2006 Apr 7;281(14):9745-54. doi: 10.1074/jbc.M513516200. Epub 2006 Feb 3. J Biol Chem. 2006. PMID: 16461769 Free PMC article.

7

Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl.

Sanjay A, Miyazaki T, Itzstein C, Purev E, Horne WC, Baron R. Sanjay A, et al. Among authors: horne wc. FEBS J. 2006 Dec;273(23):5442-56. doi: 10.1111/j.1742-4658.2006.05535.x. Epub 2006 Nov 9. FEBS J. 2006. PMID: 17094785 Free article.

8

A new method to isolate large numbers of rabbit osteoclasts and osteoclast-like cells: application to the characterization of serum response element binding proteins during osteoclast differentiation.

David JP, Neff L, Chen Y, Rincon M, Horne WC, Baron R. David JP, et al. Among authors: horne wc. J Bone Miner Res. 1998 Nov;13(11):1730-8. doi: 10.1359/jbmr.1998.13.11.1730. J Bone Miner Res. 1998. PMID: 9797482 Free article.

9

The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice.

Aoki K, Didomenico E, Sims NA, Mukhopadhyay K, Neff L, Houghton A, Amling M, Levy JB, Horne WC, Baron R. Aoki K, et al. Among authors: horne wc. Bone. 1999 Sep;25(3):261-7. doi: 10.1016/s8756-3282(99)00174-x. Bone. 1999. PMID: 10495129 Free article.

10

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility.

Sanjay A, Houghton A, Neff L, DiDomenico E, Bardelay C, Antoine E, Levy J, Gailit J, Bowtell D, Horne WC, Baron R. Sanjay A, et al. Among authors: horne wc. J Cell Biol. 2001 Jan 8;152(1):181-95. doi: 10.1083/jcb.152.1.181. J Cell Biol. 2001. PMID: 11149930 Free PMC article.

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