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Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines.
Cami-Kobeci G, Neal AP, Bradbury FA, Purington LC, Aceto MD, Harris LS, Lewis JW, Traynor JR, Husbands SM. Cami-Kobeci G, et al. Among authors: harris ls. J Med Chem. 2009 Mar 26;52(6):1546-52. doi: 10.1021/jm8015552. J Med Chem. 2009. PMID: 19253970 Free PMC article.
Synthesis and biological evaluation of 14-alkoxymorphinans. 18. N-substituted 14-phenylpropyloxymorphinan-6-ones with unanticipated agonist properties: extending the scope of common structure-activity relationships.
Greiner E, Spetea M, Krassnig R, Schüllner F, Aceto M, Harris LS, Traynor JR, Woods JH, Coop A, Schmidhammer H. Greiner E, et al. Among authors: harris ls. J Med Chem. 2003 Apr 24;46(9):1758-63. doi: 10.1021/jm021118o. J Med Chem. 2003. PMID: 12699394
Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists.
Cheng K, Kim IJ, Lee MJ, Adah SA, Raymond TJ, Bilsky EJ, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Cheng K, et al. Among authors: harris ls. Org Biomol Chem. 2007 Apr 21;5(8):1177-1190. doi: 10.1039/b618875c. Epub 2007 Mar 1. Org Biomol Chem. 2007. PMID: 17406716
Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series.
Hiebel AC, Lee YS, Bilsky E, Giuvelis D, Deschamps JR, Parrish DA, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Partilla JS, Rothman RB, Cheng K, Jacobson AE, Rice KC. Hiebel AC, et al. Among authors: harris ls. J Med Chem. 2007 Aug 9;50(16):3765-76. doi: 10.1021/jm061325e. Epub 2007 Jul 11. J Med Chem. 2007. PMID: 17625813
302 results