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A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C. Schaefer G, et al. Among authors: bostrom j. Cancer Cell. 2011 Oct 18;20(4):472-86. doi: 10.1016/j.ccr.2011.09.003. Cancer Cell. 2011. PMID: 22014573 Free article.
Translation levels control multi-spanning membrane protein expression.
Kim HS, Ernst JA, Brown C, Bostrom J, Fuh G, Lee CV, Huang A, Vandlen RL, Yansura DG. Kim HS, et al. Among authors: bostrom j. PLoS One. 2012;7(4):e35844. doi: 10.1371/journal.pone.0035844. Epub 2012 Apr 26. PLoS One. 2012. PMID: 22563408 Free PMC article.
Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.
Valerie NCK, Sanjiv K, Mortusewicz O, Zhang SM, Alam S, Pires MJ, Stigsdotter H, Rasti A, Langelier MF, Rehling D, Throup A, Purewal-Sidhu O, Desroses M, Onireti J, Wakchaure P, Almlöf I, Boström J, Bevc L, Benzi G, Stenmark P, Pascal JM, Helleday T, Page BDG, Altun M. Valerie NCK, et al. Among authors: bostrom j. Nat Commun. 2024 Dec 6;15(1):10347. doi: 10.1038/s41467-024-54415-7. Nat Commun. 2024. PMID: 39643609 Free PMC article.
Consequences of gene editing of PRLR on thermotolerance, growth, and male reproduction in cattle.
Cuellar CJ, Amaral TF, Rodriguez-Villamil P, Ongaratto F, Martinez DO, Labrecque R, Losano JDA, Estrada-Cortés E, Bostrom JR, Martins K, Rae DO, Block J, Hoorn QA, Daigneault BW, Merriam J, Lohuis M, Dikmen S, Bittar JHJ, Maia TS, Carlson DF, Larson S, Sonstegard TS, Hansen PJ. Cuellar CJ, et al. Among authors: bostrom jr. FASEB Bioadv. 2024 Jun 18;6(8):223-234. doi: 10.1096/fba.2024-00029. eCollection 2024 Aug. FASEB Bioadv. 2024. PMID: 39114445 Free PMC article.
200 results