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Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.
Haverkamp JM, Smith AM, Weinlich R, Dillon CP, Qualls JE, Neale G, Koss B, Kim Y, Bronte V, Herold MJ, Green DR, Opferman JT, Murray PJ. Haverkamp JM, et al. Among authors: neale g. Immunity. 2014 Dec 18;41(6):947-59. doi: 10.1016/j.immuni.2014.10.020. Epub 2014 Dec 11. Immunity. 2014. PMID: 25500368 Free PMC article.
TNF Counterbalances the Emergence of M2 Tumor Macrophages.
Kratochvill F, Neale G, Haverkamp JM, Van de Velde LA, Smith AM, Kawauchi D, McEvoy J, Roussel MF, Dyer MA, Qualls JE, Murray PJ. Kratochvill F, et al. Among authors: neale g. Cell Rep. 2015 Sep 22;12(11):1902-14. doi: 10.1016/j.celrep.2015.08.033. Epub 2015 Sep 10. Cell Rep. 2015. PMID: 26365184 Free PMC article.
An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens.
Meliopoulos VA, Van de Velde LA, Van de Velde NC, Karlsson EA, Neale G, Vogel P, Guy C, Sharma S, Duan S, Surman SL, Jones BG, Johnson MD, Bosio C, Jolly L, Jenkins RG, Hurwitz JL, Rosch JW, Sheppard D, Thomas PG, Murray PJ, Schultz-Cherry S. Meliopoulos VA, et al. Among authors: neale g. PLoS Pathog. 2016 Aug 9;12(8):e1005804. doi: 10.1371/journal.ppat.1005804. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27505057 Free PMC article.
T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.
Van de Velde LA, Subramanian C, Smith AM, Barron L, Qualls JE, Neale G, Alfonso-Pecchio A, Jackowski S, Rock CO, Wynn TA, Murray PJ. Van de Velde LA, et al. Among authors: neale g. J Biol Chem. 2017 Jan 6;292(1):15-30. doi: 10.1074/jbc.M116.766238. Epub 2016 Nov 30. J Biol Chem. 2017. PMID: 27903651 Free PMC article.
Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis.
Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Fukuda Y, et al. Among authors: neale g. JCI Insight. 2017 Aug 3;2(15):e92409. doi: 10.1172/jci.insight.92409. eCollection 2017 Aug 3. JCI Insight. 2017. PMID: 28768907 Free PMC article.
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat.
Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, Mosca R, Campos Y, Tillman H, Roussel MF, Andrew Weesner J, Ellen Fremuth L, Qiu X, Han MJ, Grosveld GC, d'Azzo A. Annunziata I, et al. Among authors: neale g. Nat Commun. 2019 Aug 9;10(1):3623. doi: 10.1038/s41467-019-11568-0. Nat Commun. 2019. PMID: 31399583 Free PMC article.
349 results