Osawa Y - Search Results

1

Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis.

Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA. Kodama Y, et al. Among authors: osawa y. Gastroenterology. 2009 Apr;136(4):1423-34. doi: 10.1053/j.gastro.2008.12.064. Epub 2009 Jan 6. Gastroenterology. 2009. PMID: 19249395

2

The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells.

Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D, Brenner DA. Adachi M, et al. Among authors: osawa y. Gastroenterology. 2007 Apr;132(4):1434-46. doi: 10.1053/j.gastro.2007.01.033. Epub 2007 Jan 25. Gastroenterology. 2007. PMID: 17408630

3

Tumor necrosis factor alpha-induced interleukin-8 production via NF-kappaB and phosphatidylinositol 3-kinase/Akt pathways inhibits cell apoptosis in human hepatocytes.

Osawa Y, Nagaki M, Banno Y, Brenner DA, Asano T, Nozawa Y, Moriwaki H, Nakashima S. Osawa Y, et al. Infect Immun. 2002 Nov;70(11):6294-301. doi: 10.1128/IAI.70.11.6294-6301.2002. Infect Immun. 2002. PMID: 12379708 Free PMC article.

4

Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation.

Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, Nakashima S. Osawa Y, et al. J Immunol. 2003 Apr 15;170(8):4053-60. doi: 10.4049/jimmunol.170.8.4053. J Immunol. 2003. PMID: 12682234

5

Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.

Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H. Imose M, et al. Among authors: osawa y. Liver Int. 2003 Oct;23(5):386-96. doi: 10.1034/j.1478-3231.2003.00867.x. Liver Int. 2003. PMID: 14708901

6

Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liver.

Osawa Y, Hannun YA, Proia RL, Brenner DA. Osawa Y, et al. Hepatology. 2005 Dec;42(6):1320-8. doi: 10.1002/hep.20967. Hepatology. 2005. PMID: 16317686

7

Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression.

Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. Osawa Y, et al. FASEB J. 2011 Apr;25(4):1133-44. doi: 10.1096/fj.10-168351. Epub 2010 Dec 16. FASEB J. 2011. PMID: 21163859 Free PMC article.

8

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha.

Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA. Osawa Y, et al. J Biol Chem. 2005 Jul 29;280(30):27879-87. doi: 10.1074/jbc.M503002200. Epub 2005 Jun 9. J Biol Chem. 2005. PMID: 15946935 Free article.

9

Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB.

Miura K, Yoshino R, Hirai Y, Goto T, Ohshima S, Mikami K, Yoneyama K, Watanabe D, Sato M, Senoo H, Kodama Y, Osawa Y, Brenner DA, Watanabe S. Miura K, et al. Among authors: osawa y. J Hepatol. 2007 Dec;47(6):834-43. doi: 10.1016/j.jhep.2007.07.024. Epub 2007 Sep 25. J Hepatol. 2007. PMID: 17935821

10

Anandamide induces necrosis in primary hepatic stellate cells.

Siegmund SV, Uchinami H, Osawa Y, Brenner DA, Schwabe RF. Siegmund SV, et al. Among authors: osawa y. Hepatology. 2005 May;41(5):1085-95. doi: 10.1002/hep.20667. Hepatology. 2005. PMID: 15841466

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