Carroll JB - Search Results

1

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.

Joshi PR, Wu NP, André VM, Cummings DM, Cepeda C, Joyce JA, Carroll JB, Leavitt BR, Hayden MR, Levine MS, Bamford NS. Joshi PR, et al. Among authors: carroll jb. J Neurosci. 2009 Feb 25;29(8):2414-27. doi: 10.1523/JNEUROSCI.5687-08.2009. J Neurosci. 2009. PMID: 19244517 Free PMC article.

2

Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.

Van Raamsdonk JM, Metzler M, Slow E, Pearson J, Schwab C, Carroll J, Graham RK, Leavitt BR, Hayden MR. Van Raamsdonk JM, et al. Neurobiol Dis. 2007 Apr;26(1):189-200. doi: 10.1016/j.nbd.2006.12.010. Epub 2006 Dec 29. Neurobiol Dis. 2007. PMID: 17276692

3

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Valenza M, Carroll JB, Leoni V, Bertram LN, Björkhem I, Singaraja RR, Di Donato S, Lutjohann D, Hayden MR, Cattaneo E. Valenza M, et al. Among authors: carroll jb. Hum Mol Genet. 2007 Sep 15;16(18):2187-98. doi: 10.1093/hmg/ddm170. Epub 2007 Jul 5. Hum Mol Genet. 2007. PMID: 17613541

4

Automated deformation analysis in the YAC128 Huntington disease mouse model.

Lerch JP, Carroll JB, Spring S, Bertram LN, Schwab C, Hayden MR, Henkelman RM. Lerch JP, et al. Among authors: carroll jb. Neuroimage. 2008 Jan 1;39(1):32-9. doi: 10.1016/j.neuroimage.2007.08.033. Epub 2007 Aug 31. Neuroimage. 2008. PMID: 17942324

5

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease.

Lerch JP, Carroll JB, Dorr A, Spring S, Evans AC, Hayden MR, Sled JG, Henkelman RM. Lerch JP, et al. Among authors: carroll jb. Neuroimage. 2008 Jun;41(2):243-51. doi: 10.1016/j.neuroimage.2008.02.019. Epub 2008 Feb 26. Neuroimage. 2008. PMID: 18387826

6

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus.

Warby SC, Doty CN, Graham RK, Carroll JB, Yang YZ, Singaraja RR, Overall CM, Hayden MR. Warby SC, et al. Among authors: carroll jb. Hum Mol Genet. 2008 Aug 1;17(15):2390-404. doi: 10.1093/hmg/ddn139. Epub 2008 Apr 29. Hum Mol Genet. 2008. PMID: 18445618

7

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.

Warby SC, Montpetit A, Hayden AR, Carroll JB, Butland SL, Visscher H, Collins JA, Semaka A, Hudson TJ, Hayden MR. Warby SC, et al. Among authors: carroll jb. Am J Hum Genet. 2009 Mar;84(3):351-66. doi: 10.1016/j.ajhg.2009.02.003. Epub 2009 Feb 26. Am J Hum Genet. 2009. PMID: 19249009 Free PMC article.

8

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes.

Valenza M, Leoni V, Karasinska JM, Petricca L, Fan J, Carroll J, Pouladi MA, Fossale E, Nguyen HP, Riess O, MacDonald M, Wellington C, DiDonato S, Hayden M, Cattaneo E. Valenza M, et al. J Neurosci. 2010 Aug 11;30(32):10844-50. doi: 10.1523/JNEUROSCI.0917-10.2010. J Neurosci. 2010. PMID: 20702713 Free PMC article.

9

Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.

Graham RK, Deng Y, Carroll J, Vaid K, Cowan C, Pouladi MA, Metzler M, Bissada N, Wang L, Faull RL, Gray M, Yang XW, Raymond LA, Hayden MR. Graham RK, et al. J Neurosci. 2010 Nov 10;30(45):15019-29. doi: 10.1523/JNEUROSCI.2071-10.2010. J Neurosci. 2010. PMID: 21068307 Free PMC article.

10

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease.

Carroll JB, Lerch JP, Franciosi S, Spreeuw A, Bissada N, Henkelman RM, Hayden MR. Carroll JB, et al. Neurobiol Dis. 2011 Jul;43(1):257-65. doi: 10.1016/j.nbd.2011.03.018. Epub 2011 Mar 31. Neurobiol Dis. 2011. PMID: 21458571

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