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Page 1
Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.
Brand OJ, Barrett JC, Simmonds MJ, Newby PR, McCabe CJ, Bruce CK, Kysela B, Carr-Smith JD, Brix T, Hunt PJ, Wiersinga WM, Hegedüs L, Connell J, Wass JA, Franklyn JA, Weetman AP, Heward JM, Gough SC. Brand OJ, et al. Among authors: wiersinga wm. Hum Mol Genet. 2009 May 1;18(9):1704-13. doi: 10.1093/hmg/ddp087. Epub 2009 Feb 25. Hum Mol Genet. 2009. PMID: 19244275
Association of the TSHR gene with Graves' disease: the first disease specific locus.
Dechairo BM, Zabaneh D, Collins J, Brand O, Dawson GJ, Green AP, Mackay I, Franklyn JA, Connell JM, Wass JA, Wiersinga WM, Hegedus L, Brix T, Robinson BG, Hunt PJ, Weetman AP, Carey AH, Gough SC. Dechairo BM, et al. Among authors: wiersinga wm. Eur J Hum Genet. 2005 Nov;13(11):1223-30. doi: 10.1038/sj.ejhg.5201485. Eur J Hum Genet. 2005. PMID: 16106256
Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe.
Hamilton A, Newby PR, Carr-Smith JD, Disanto G, Allahabadia A, Armitage M, Brix TH, Chatterjee K, Connell JM, Hegedüs L, Hunt PJ, Lazarus JH, Pearce SH, Robinson BG, Taylor JC, Vaidya B, Wass JA, Wiersinga WM, Weetman AP, Ramagopalan SV, Franklyn JA, Gough SC, Simmonds MJ. Hamilton A, et al. Among authors: wiersinga wm. J Clin Endocrinol Metab. 2014 Aug;99(8):E1459-65. doi: 10.1210/jc.2014-1270. Epub 2014 May 19. J Clin Endocrinol Metab. 2014. PMID: 24840812 Free article.
Predictive score for the development or progression of Graves' orbitopathy in patients with newly diagnosed Graves' hyperthyroidism.
Wiersinga W, Žarković M, Bartalena L, Donati S, Perros P, Okosieme O, Morris D, Fichter N, Lareida J, von Arx G, Daumerie C, Burlacu MC, Kahaly G, Pitz S, Beleslin B, Ćirić J, Ayvaz G, Konuk O, Törüner FB, Salvi M, Covelli D, Curro N, Hegedüs L, Brix T; EUGOGO (European Group on Graves’ Orbitopathy). Wiersinga W, et al. Eur J Endocrinol. 2018 Jun;178(6):635-643. doi: 10.1530/EJE-18-0039. Epub 2018 Apr 12. Eur J Endocrinol. 2018. PMID: 29650691
PREGO (presentation of Graves' orbitopathy) study: changes in referral patterns to European Group On Graves' Orbitopathy (EUGOGO) centres over the period from 2000 to 2012.
Perros P, Žarković M, Azzolini C, Ayvaz G, Baldeschi L, Bartalena L, Boschi A, Bournaud C, Brix TH, Covelli D, Ćirić S, Daumerie C, Eckstein A, Fichter N, Führer D, Hegedüs L, Kahaly GJ, Konuk O, Lareida J, Lazarus J, Leo M, Mathiopoulou L, Menconi F, Morris D, Okosieme O, Orgiazzi J, Pitz S, Salvi M, Vardanian-Vartin C, Wiersinga W, Bernard M, Clarke L, Currò N, Dayan C, Dickinson J, Knežević M, Lane C, Marcocci C, Marinò M, Möller L, Nardi M, Neoh C, Pearce S, von Arx G, Törüner FB. Perros P, et al. Br J Ophthalmol. 2015 Nov;99(11):1531-5. doi: 10.1136/bjophthalmol-2015-306733. Epub 2015 May 7. Br J Ophthalmol. 2015. PMID: 25953846
Asymmetry indicates more severe and active disease in Graves' orbitopathy: results from a prospective cross-sectional multicentre study.
Perros P, Žarković MP, Panagiotou GC, Azzolini C, Ayvaz G, Baldeschi L, Bartalena L, Boschi AM, Nardi M, Brix TH, Covelli D, Daumerie C, Eckstein AK, Fichter N, Ćirić S, Hegedüs L, Kahaly GJ, Konuk O, Lareida JJ, Okosieme OE, Leo M, Mathiopoulou L, Clarke L, Menconi F, Morris DS, Orgiazzi J, Pitz S, Salvi M, Muller I, Knežević M, Wiersinga WM, Currò N, Dayan CM, Marcocci C, Marinò M, Möller L, Pearce SH, Törüner F, Bernard M; European Group on Graves’ Orbitopathy. Perros P, et al. Among authors: wiersinga wm. J Endocrinol Invest. 2020 Dec;43(12):1717-1722. doi: 10.1007/s40618-020-01258-w. Epub 2020 May 30. J Endocrinol Invest. 2020. PMID: 32474767 Free PMC article.
Antithyroid drugs in Graves' hyperthyroidism: differences between "block and replace" and "titration" regimes in frequency of euthyroidism and Graves' orbitopathy during treatment.
Žarković M, Wiersinga W, Perros P, Bartalena L, Donati S, Okosieme O, Morris D, Fichter N, Lareida J, Daumerie C, Burlacu MC, Kahaly GJ, Pitz S, Beleslin B, Ćirić J, Ayvaz G, Konuk O, Törüner FB, Salvi M, Covelli D, Curro N, Hegedüs L, Brix T; EUGOGO (European Group on Graves’ Orbitopathy). Žarković M, et al. J Endocrinol Invest. 2021 Feb;44(2):371-378. doi: 10.1007/s40618-020-01320-7. Epub 2020 Jun 10. J Endocrinol Invest. 2021. PMID: 32524368
Complete inhibition of rhTSH-, Graves' disease IgG-, and M22-induced cAMP production in differentiated orbital fibroblasts by a low-molecular-weight TSHR antagonist.
van Zeijl CJ, van Koppen CJ, Surovtseva OV, de Gooyer ME, Plate R, Conti P, Karstens WJ, Timmers M, Saeed P, Wiersinga WM, Miltenburg AM, Fliers E, Boelen A. van Zeijl CJ, et al. Among authors: wiersinga wm. J Clin Endocrinol Metab. 2012 May;97(5):E781-5. doi: 10.1210/jc.2011-2931. Epub 2012 Mar 14. J Clin Endocrinol Metab. 2012. PMID: 22419705
Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathways.
van Zeijl CJ, Fliers E, van Koppen CJ, Surovtseva OV, de Gooyer ME, Mourits MP, Wiersinga WM, Miltenburg AM, Boelen A. van Zeijl CJ, et al. Among authors: wiersinga wm. Thyroid. 2011 Feb;21(2):169-76. doi: 10.1089/thy.2010.0123. Epub 2010 Oct 18. Thyroid. 2011. PMID: 20954819
435 results