Roman LJ - Search Results

1

Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy.

Ji H, Tan S, Igarashi J, Li H, Derrick M, Martásek P, Roman LJ, Vásquez-Vivar J, Poulos TL, Silverman RB. Ji H, et al. Among authors: roman lj. Ann Neurol. 2009 Feb;65(2):209-17. doi: 10.1002/ana.21555. Ann Neurol. 2009. PMID: 19235180 Free PMC article.

2

Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.

Hah JM, Martásek P, Roman LJ, Silverman RB. Hah JM, et al. Among authors: roman lj. J Med Chem. 2003 Apr 24;46(9):1661-9. doi: 10.1021/jm0202932. J Med Chem. 2003. PMID: 12699384

3

Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.

Gómez-Vidal JA, Martásek P, Roman LJ, Silverman RB. Gómez-Vidal JA, et al. Among authors: roman lj. J Med Chem. 2004 Jan 29;47(3):703-10. doi: 10.1021/jm030297m. J Med Chem. 2004. PMID: 14736250

4

Design, synthesis, and biological testing of potential heme-coordinating nitric oxide synthase inhibitors.

Litzinger EA, Martásek P, Roman LJ, Silverman RB. Litzinger EA, et al. Among authors: roman lj. Bioorg Med Chem. 2006 May 1;14(9):3185-98. doi: 10.1016/j.bmc.2005.12.043. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431112

5

Hydroxyl-terminated peptidomimetic inhibitors of neuronal nitric oxide synthase.

Mbadugha BN, Seo J, Ji H, Martásek P, Roman LJ, Shea TM, Li H, Poulos TL, Silverman RB. Mbadugha BN, et al. Among authors: roman lj. Bioorg Med Chem. 2006 Jun 1;14(11):3681-90. doi: 10.1016/j.bmc.2006.01.044. Epub 2006 Feb 9. Bioorg Med Chem. 2006. PMID: 16480878

6

Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.

Ji H, Gómez-Vidal JA, Martasek P, Roman LJ, Silverman RB. Ji H, et al. Among authors: roman lj. J Med Chem. 2006 Oct 19;49(21):6254-63. doi: 10.1021/jm0604124. J Med Chem. 2006. PMID: 17034131 Free PMC article.

7

Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.

Seo J, Martásek P, Roman LJ, Silverman RB. Seo J, et al. Among authors: roman lj. Bioorg Med Chem. 2007 Mar 1;15(5):1928-38. doi: 10.1016/j.bmc.2007.01.001. Epub 2007 Jan 4. Bioorg Med Chem. 2007. PMID: 17239601 Free PMC article.

8

Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water.

Seo J, Igarashi J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Seo J, et al. Among authors: roman lj. J Med Chem. 2007 May 3;50(9):2089-99. doi: 10.1021/jm061305c. Epub 2007 Apr 11. J Med Chem. 2007. PMID: 17425297 Free PMC article.

9

Hydroxyethylene isosteres of selective neuronal nitric oxide synthase inhibitors.

Erdal EP, Martásek P, Roman LJ, Silverman RB. Erdal EP, et al. Among authors: roman lj. Bioorg Med Chem. 2007 Sep 15;15(18):6096-108. doi: 10.1016/j.bmc.2007.06.038. Epub 2007 Jun 23. Bioorg Med Chem. 2007. PMID: 17614291 Free PMC article.

10

Minimal pharmacophoric elements and fragment hopping, an approach directed at molecular diversity and isozyme selectivity. Design of selective neuronal nitric oxide synthase inhibitors.

Ji H, Stanton BZ, Igarashi J, Li H, Martásek P, Roman LJ, Poulos TL, Silverman RB. Ji H, et al. Among authors: roman lj. J Am Chem Soc. 2008 Mar 26;130(12):3900-14. doi: 10.1021/ja0772041. Epub 2008 Mar 6. J Am Chem Soc. 2008. PMID: 18321097 Free PMC article.

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