Altomare DA - Search Results

1

Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice.

Altomare DA, Menges CW, Pei J, Zhang L, Skele-Stump KL, Carbone M, Kane AB, Testa JR. Altomare DA, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3420-5. doi: 10.1073/pnas.0808816106. Epub 2009 Feb 17. Proc Natl Acad Sci U S A. 2009. PMID: 19223589 Free PMC article.

2

FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis.

Menges CW, Altomare DA, Testa JR. Menges CW, et al. Among authors: altomare da. Cell Cycle. 2009 Aug 15;8(16):2528-34. doi: 10.4161/cc.8.16.9280. Epub 2009 Aug 16. Cell Cycle. 2009. PMID: 19597341 Free PMC article. Review.

3

Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.

Altomare DA, Menges CW, Xu J, Pei J, Zhang L, Tadevosyan A, Neumann-Domer E, Liu Z, Carbone M, Chudoba I, Klein-Szanto AJ, Testa JR. Altomare DA, et al. PLoS One. 2011 Apr 19;6(4):e18828. doi: 10.1371/journal.pone.0018828. PLoS One. 2011. PMID: 21526190 Free PMC article.

4

Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis.

Menges CW, Kadariya Y, Altomare D, Talarchek J, Neumann-Domer E, Wu Y, Xiao GH, Shapiro IM, Kolev VN, Pachter JA, Klein-Szanto AJ, Testa JR. Menges CW, et al. Cancer Res. 2014 Feb 15;74(4):1261-1271. doi: 10.1158/0008-5472.CAN-13-2062. Epub 2013 Dec 26. Cancer Res. 2014. PMID: 24371224 Free PMC article.

5

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.

Altomare DA, You H, Xiao GH, Ramos-Nino ME, Skele KL, De Rienzo A, Jhanwar SC, Mossman BT, Kane AB, Testa JR. Altomare DA, et al. Oncogene. 2005 Sep 8;24(40):6080-9. doi: 10.1038/sj.onc.1208744. Oncogene. 2005. PMID: 15897870

6

A mouse model recapitulating molecular features of human mesothelioma.

Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR. Altomare DA, et al. Cancer Res. 2005 Sep 15;65(18):8090-5. doi: 10.1158/0008-5472.CAN-05-2312. Cancer Res. 2005. PMID: 16166281

7

Perturbations of the AKT signaling pathway in human cancer.

Altomare DA, Testa JR. Altomare DA, et al. Oncogene. 2005 Nov 14;24(50):7455-64. doi: 10.1038/sj.onc.1209085. Oncogene. 2005. PMID: 16288292 Review.

8

Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.

Tan Y, You H, Wu C, Altomare DA, Testa JR. Tan Y, et al. Among authors: altomare da. J Biol Chem. 2010 Feb 26;285(9):6377-89. doi: 10.1074/jbc.M109.068452. Epub 2009 Dec 29. J Biol Chem. 2010. PMID: 20040596 Free PMC article.

9

Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent.

Altomare DA, Rybak SM, Pei J, Maizel JV, Cheung M, Testa JR, Shogen K. Altomare DA, et al. BMC Cancer. 2010 Feb 5;10:34. doi: 10.1186/1471-2407-10-34. BMC Cancer. 2010. PMID: 20137089 Free PMC article.

10

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma.

Cheng JQ, Jhanwar SC, Klein WM, Bell DW, Lee WC, Altomare DA, Nobori T, Olopade OI, Buckler AJ, Testa JR. Cheng JQ, et al. Among authors: altomare da. Cancer Res. 1994 Nov 1;54(21):5547-51. Cancer Res. 1994. PMID: 7923195

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