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Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.
Patterson VL, Damrau C, Paudyal A, Reeve B, Grimes DT, Stewart ME, Williams DJ, Siggers P, Greenfield A, Murdoch JN. Patterson VL, et al. Among authors: murdoch jn. Hum Mol Genet. 2009 May 15;18(10):1719-39. doi: 10.1093/hmg/ddp075. Epub 2009 Feb 17. Hum Mol Genet. 2009. PMID: 19223390 Free PMC article.
The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.
Paudyal A, Damrau C, Patterson VL, Ermakov A, Formstone C, Lalanne Z, Wells S, Lu X, Norris DP, Dean CH, Henderson DJ, Murdoch JN. Paudyal A, et al. Among authors: murdoch jn. BMC Dev Biol. 2010 Aug 12;10:87. doi: 10.1186/1471-213X-10-87. BMC Dev Biol. 2010. PMID: 20704721 Free PMC article.
Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung.
Yates LL, Schnatwinkel C, Hazelwood L, Chessum L, Paudyal A, Hilton H, Romero MR, Wilde J, Bogani D, Sanderson J, Formstone C, Murdoch JN, Niswander LA, Greenfield A, Dean CH. Yates LL, et al. Among authors: murdoch jn. Dev Biol. 2013 Jan 15;373(2):267-80. doi: 10.1016/j.ydbio.2012.11.012. Epub 2012 Nov 27. Dev Biol. 2013. PMID: 23195221 Free PMC article.
The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.
Glasco DM, Sittaramane V, Bryant W, Fritzsch B, Sawant A, Paudyal A, Stewart M, Andre P, Cadete Vilhais-Neto G, Yang Y, Song MR, Murdoch JN, Chandrasekhar A. Glasco DM, et al. Among authors: murdoch jn. Dev Biol. 2012 Sep 15;369(2):211-22. doi: 10.1016/j.ydbio.2012.06.021. Epub 2012 Jul 4. Dev Biol. 2012. PMID: 22771245 Free PMC article.
The genetic basis of mammalian neurulation.
Copp AJ, Greene ND, Murdoch JN. Copp AJ, et al. Among authors: murdoch jn. Nat Rev Genet. 2003 Oct;4(10):784-93. doi: 10.1038/nrg1181. Nat Rev Genet. 2003. PMID: 13679871 Review.
40 results