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In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept.
Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. Ioannou Y, et al. Among authors: papalardo e. J Thromb Haemost. 2009 May;7(5):833-42. doi: 10.1111/j.1538-7836.2009.03316.x. Epub 2009 Feb 12. J Thromb Haemost. 2009. PMID: 19220729 Free article.
PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.
McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. McDonnell TCR, et al. Among authors: papalardo e. Front Immunol. 2018 Oct 22;9:2413. doi: 10.3389/fimmu.2018.02413. eCollection 2018. Front Immunol. 2018. PMID: 30405613 Free PMC article.
Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome.
Romay-Penabad Z, Aguilar-Valenzuela R, Urbanus RT, Derksen RH, Pennings MT, Papalardo E, Shilagard T, Vargas G, Hwang Y, de Groot PG, Pierangeli SS. Romay-Penabad Z, et al. Among authors: papalardo e. Blood. 2011 Jan 27;117(4):1408-14. doi: 10.1182/blood-2010-07-299099. Epub 2010 Nov 30. Blood. 2011. PMID: 21119114 Free PMC article.
Statins for the treatment of antiphospholipid syndrome?
Jajoria P, Murthy V, Papalardo E, Romay-Penabad Z, Gleason C, Pierangeli SS. Jajoria P, et al. Among authors: papalardo e. Ann N Y Acad Sci. 2009 Sep;1173:736-45. doi: 10.1111/j.1749-6632.2009.04815.x. Ann N Y Acad Sci. 2009. PMID: 19758223 Clinical Trial.
Value of isolated IgA anti-β2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome.
Murthy V, Willis R, Romay-Penabad Z, Ruiz-Limón P, Martínez-Martínez LA, Jatwani S, Jajoria P, Seif A, Alarcón GS, Papalardo E, Liu J, Vilá LM, McGwin G Jr, McNearney TA, Maganti R, Sunkureddi P, Parekh T, Tarantino M, Akhter E, Fang H, Gonzalez EB, Binder WR, Norman GL, Shums Z, Teodorescu M, Reveille JD, Petri M, Pierangeli SS. Murthy V, et al. Among authors: papalardo e. Arthritis Rheum. 2013 Dec;65(12):3186-93. doi: 10.1002/art.38131. Arthritis Rheum. 2013. PMID: 23983008 Free PMC article.
Major Histocompatibility Complex Class II Alleles Influence Induction of Pathogenic Antiphospholipid Antibodies in a Mouse Model of Thrombosis.
Papalardo E, Romay-Penabad Z, Willis R, Christadoss P, Carrera-Marin AL, Reyes-Maldonado E, Rudrangi R, Alfieri-Papalardo S, Garcia-Latorre E, Blank M, Pierangeli S, Brasier AR, Gonzalez EB. Papalardo E, et al. Arthritis Rheumatol. 2017 Oct;69(10):2052-2061. doi: 10.1002/art.40195. Epub 2017 Sep 12. Arthritis Rheumatol. 2017. PMID: 28666081
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