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In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept.
Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. Ioannou Y, et al. J Thromb Haemost. 2009 May;7(5):833-42. doi: 10.1111/j.1538-7836.2009.03316.x. Epub 2009 Feb 12. J Thromb Haemost. 2009. PMID: 19220729 Free article.
Laboratory tests for the antiphospholipid syndrome.
Pericleous C, Ripoll VM, Giles I, Ioannou Y. Pericleous C, et al. Among authors: ioannou y. Methods Mol Biol. 2014;1134:221-35. doi: 10.1007/978-1-4939-0326-9_17. Methods Mol Biol. 2014. PMID: 24497366
Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis.
Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS. Pericleous C, et al. Among authors: ioannou y. Rheumatology (Oxford). 2015 Apr;54(4):722-7. doi: 10.1093/rheumatology/keu360. Epub 2014 Sep 30. Rheumatology (Oxford). 2015. PMID: 25273993 Free PMC article.
PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome.
McDonnell TCR, Willis R, Pericleous C, Ripoll VM, Giles IP, Isenberg DA, Brasier AR, Gonzalez EB, Papalardo E, Romay-Penabad Z, Jamaluddin M, Ioannou Y, Rahman A. McDonnell TCR, et al. Among authors: ioannou y. Front Immunol. 2018 Oct 22;9:2413. doi: 10.3389/fimmu.2018.02413. eCollection 2018. Front Immunol. 2018. PMID: 30405613 Free PMC article.
194 results