Linehan JM - Search Results

1

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins.

Asante EA, Gowland I, Grimshaw A, Linehan JM, Smidak M, Houghton R, Osiguwa O, Tomlinson A, Joiner S, Brandner S, Wadsworth JDF, Collinge J. Asante EA, et al. Among authors: linehan jm. J Gen Virol. 2009 Mar;90(Pt 3):546-558. doi: 10.1099/vir.0.007930-0. J Gen Virol. 2009. PMID: 19218199 Free PMC article.

2

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein.

Asante EA, Linehan JM, Desbruslais M, Joiner S, Gowland I, Wood AL, Welch J, Hill AF, Lloyd SE, Wadsworth JD, Collinge J. Asante EA, et al. Among authors: linehan jm. EMBO J. 2002 Dec 2;21(23):6358-66. doi: 10.1093/emboj/cdf653. EMBO J. 2002. PMID: 12456643 Free PMC article.

3

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

Mallucci G, Dickinson A, Linehan J, Klöhn PC, Brandner S, Collinge J. Mallucci G, et al. Science. 2003 Oct 31;302(5646):871-4. doi: 10.1126/science.1090187. Science. 2003. PMID: 14593181

4

Identification and characterization of a novel mouse prion gene allele.

Lloyd SE, Thompson SR, Beck JA, Linehan JM, Wadsworth JD, Brandner S, Collinge J, Fisher EM. Lloyd SE, et al. Among authors: linehan jm. Mamm Genome. 2004 May;15(5):383-9. doi: 10.1007/s00335-004-3041-5. Mamm Genome. 2004. PMID: 15170227

5

Characterization of two distinct prion strains derived from bovine spongiform encephalopathy transmissions to inbred mice.

Lloyd SE, Linehan JM, Desbruslais M, Joiner S, Buckell J, Brandner S, Wadsworth JDF, Collinge J. Lloyd SE, et al. Among authors: linehan jm. J Gen Virol. 2004 Aug;85(Pt 8):2471-2478. doi: 10.1099/vir.0.79889-0. J Gen Virol. 2004. PMID: 15269389

6

Analysis of 2000 consecutive UK tonsillectomy specimens for disease-related prion protein.

Frosh A, Smith LC, Jackson CJ, Linehan JM, Brandner S, Wadsworth JD, Collinge J. Frosh A, et al. Among authors: linehan jm. Lancet. 2004 Oct 2-8;364(9441):1260-2. doi: 10.1016/S0140-6736(04)17143-2. Lancet. 2004. PMID: 15464187

7

Human prion protein with valine 129 prevents expression of variant CJD phenotype.

Wadsworth JD, Asante EA, Desbruslais M, Linehan JM, Joiner S, Gowland I, Welch J, Stone L, Lloyd SE, Hill AF, Brandner S, Collinge J. Wadsworth JD, et al. Among authors: linehan jm. Science. 2004 Dec 3;306(5702):1793-6. doi: 10.1126/science.1103932. Epub 2004 Nov 11. Science. 2004. PMID: 15539564

8

PrP glycoforms are associated in a strain-specific ratio in native PrPSc.

Khalili-Shirazi A, Summers L, Linehan J, Mallinson G, Anstee D, Hawke S, Jackson GS, Collinge J. Khalili-Shirazi A, et al. J Gen Virol. 2005 Sep;86(Pt 9):2635-2644. doi: 10.1099/vir.0.80375-0. J Gen Virol. 2005. PMID: 16099923

9

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes.

O'Doherty A, Ruf S, Mulligan C, Hildreth V, Errington ML, Cooke S, Sesay A, Modino S, Vanes L, Hernandez D, Linehan JM, Sharpe PT, Brandner S, Bliss TV, Henderson DJ, Nizetic D, Tybulewicz VL, Fisher EM. O'Doherty A, et al. Among authors: linehan jm. Science. 2005 Sep 23;309(5743):2033-7. doi: 10.1126/science.1114535. Science. 2005. PMID: 16179473 Free PMC article.

10

Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.

Wadsworth JD, Joiner S, Linehan JM, Cooper S, Powell C, Mallinson G, Buckell J, Gowland I, Asante EA, Budka H, Brandner S, Collinge J. Wadsworth JD, et al. Among authors: linehan jm. Brain. 2006 Jun;129(Pt 6):1557-69. doi: 10.1093/brain/awl076. Epub 2006 Apr 5. Brain. 2006. PMID: 16597650

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