Cane DE - Search Results

1

Revisiting the modularity of modular polyketide synthases.

Khosla C, Kapur S, Cane DE. Khosla C, et al. Among authors: cane de. Curr Opin Chem Biol. 2009 Apr;13(2):135-43. doi: 10.1016/j.cbpa.2008.12.018. Epub 2009 Feb 11. Curr Opin Chem Biol. 2009. PMID: 19217343 Free PMC article. Review.

2

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.

Chen AY, Schnarr NA, Kim CY, Cane DE, Khosla C. Chen AY, et al. Among authors: cane de. J Am Chem Soc. 2006 Mar 8;128(9):3067-74. doi: 10.1021/ja058093d. J Am Chem Soc. 2006. PMID: 16506788 Free PMC article.

3

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

Tang Y, Kim CY, Mathews II, Cane DE, Khosla C. Tang Y, et al. Among authors: cane de. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. doi: 10.1073/pnas.0601924103. Epub 2006 Jul 14. Proc Natl Acad Sci U S A. 2006. PMID: 16844787 Free PMC article.

4

Structure and mechanism of the 6-deoxyerythronolide B synthase.

Khosla C, Tang Y, Chen AY, Schnarr NA, Cane DE. Khosla C, et al. Among authors: cane de. Annu Rev Biochem. 2007;76:195-221. doi: 10.1146/annurev.biochem.76.053105.093515. Annu Rev Biochem. 2007. PMID: 17328673 Review.

5

Structure-based dissociation of a type I polyketide synthase module.

Chen AY, Cane DE, Khosla C. Chen AY, et al. Among authors: cane de. Chem Biol. 2007 Jul;14(7):784-92. doi: 10.1016/j.chembiol.2007.05.015. Chem Biol. 2007. PMID: 17656315 Free PMC article.

6

Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase.

Tang Y, Chen AY, Kim CY, Cane DE, Khosla C. Tang Y, et al. Among authors: cane de. Chem Biol. 2007 Aug;14(8):931-43. doi: 10.1016/j.chembiol.2007.07.012. Chem Biol. 2007. PMID: 17719492 Free PMC article.

7

Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase.

Kapur S, Worthington A, Tang Y, Cane DE, Burkart MD, Khosla C. Kapur S, et al. Among authors: cane de. Bioorg Med Chem Lett. 2008 May 15;18(10):3034-8. doi: 10.1016/j.bmcl.2008.01.073. Epub 2008 Jan 24. Bioorg Med Chem Lett. 2008. PMID: 18243693 Free PMC article.

8

Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.

Castonguay R, Valenzano CR, Chen AY, Keatinge-Clay A, Khosla C, Cane DE. Castonguay R, et al. Among authors: cane de. J Am Chem Soc. 2008 Sep 3;130(35):11598-9. doi: 10.1021/ja804453p. Epub 2008 Aug 12. J Am Chem Soc. 2008. PMID: 18693734 Free PMC article.

9

Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.

Wong FT, Chen AY, Cane DE, Khosla C. Wong FT, et al. Among authors: cane de. Biochemistry. 2010 Jan 12;49(1):95-102. doi: 10.1021/bi901826g. Biochemistry. 2010. PMID: 19921859 Free PMC article.

10

Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase.

Kapur S, Chen AY, Cane DE, Khosla C. Kapur S, et al. Among authors: cane de. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22066-71. doi: 10.1073/pnas.1014081107. Epub 2010 Dec 2. Proc Natl Acad Sci U S A. 2010. PMID: 21127271 Free PMC article.

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