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HECTD2 is associated with susceptibility to mouse and human prion disease.
Lloyd SE, Maytham EG, Pota H, Grizenkova J, Molou E, Uphill J, Hummerich H, Whitfield J, Alpers MP, Mead S, Collinge J. Lloyd SE, et al. Among authors: alpers mp. PLoS Genet. 2009 Feb;5(2):e1000383. doi: 10.1371/journal.pgen.1000383. Epub 2009 Feb 13. PLoS Genet. 2009. PMID: 19214206 Free PMC article.
A novel protective prion protein variant that colocalizes with kuru exposure.
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Campbell T, Al-Dujaily H, Hummerich H, Beck J, Mein CA, Verzilli C, Whittaker J, Alpers MP, Collinge J. Mead S, et al. Among authors: alpers mp. N Engl J Med. 2009 Nov 19;361(21):2056-65. doi: 10.1056/NEJMoa0809716. N Engl J Med. 2009. PMID: 19923577 Free article.
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, Rückert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J. Mead S, et al. Among authors: alpers mp. Hum Mol Genet. 2012 Apr 15;21(8):1897-906. doi: 10.1093/hmg/ddr607. Epub 2011 Dec 30. Hum Mol Genet. 2012. PMID: 22210626 Free PMC article.
A naturally occurring variant of the human prion protein completely prevents prion disease.
Asante EA, Smidak M, Grimshaw A, Houghton R, Tomlinson A, Jeelani A, Jakubcova T, Hamdan S, Richard-Londt A, Linehan JM, Brandner S, Alpers M, Whitfield J, Mead S, Wadsworth JD, Collinge J. Asante EA, et al. Nature. 2015 Jun 25;522(7557):478-81. doi: 10.1038/nature14510. Epub 2015 Jun 10. Nature. 2015. PMID: 26061765 Free PMC article.
Mortuary rites of the South Fore and kuru.
Whitfield JT, Pako WH, Collinge J, Alpers MP. Whitfield JT, et al. Among authors: alpers mp. Philos Trans R Soc Lond B Biol Sci. 2008 Nov 27;363(1510):3721-4. doi: 10.1098/rstb.2008.0074. Philos Trans R Soc Lond B Biol Sci. 2008. PMID: 18849288 Free PMC article.
Genetic susceptibility, evolution and the kuru epidemic.
Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Beck J, Campbell T, Al-Dujaily H, Hummerich H, Alpers MP, Collinge J. Mead S, et al. Among authors: alpers mp. Philos Trans R Soc Lond B Biol Sci. 2008 Nov 27;363(1510):3741-6. doi: 10.1098/rstb.2008.0087. Philos Trans R Soc Lond B Biol Sci. 2008. PMID: 18849290 Free PMC article.
Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.
Mead S, Poulter M, Uphill J, Beck J, Whitfield J, Webb TE, Campbell T, Adamson G, Deriziotis P, Tabrizi SJ, Hummerich H, Verzilli C, Alpers MP, Whittaker JC, Collinge J. Mead S, et al. Among authors: alpers mp. Lancet Neurol. 2009 Jan;8(1):57-66. doi: 10.1016/S1474-4422(08)70265-5. Lancet Neurol. 2009. PMID: 19081515 Free PMC article.
282 results