Hofmann U - Search Results

1

A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes.

Turpeinen M, Hofmann U, Klein K, Mürdter T, Schwab M, Zanger UM. Turpeinen M, et al. Among authors: hofmann u. Drug Metab Dispos. 2009 May;37(5):1017-24. doi: 10.1124/dmd.108.025700. Epub 2009 Feb 9. Drug Metab Dispos. 2009. PMID: 19204080

2

Identification of thiodiglycolic acid, thiodiglycolic acid sulfoxide, and (3-carboxymethylthio)lactic acid as major human biotransformation products of S-carboxymethyl-L-cysteine.

Hofmann U, Eichelbaum M, Seefried S, Meese CO. Hofmann U, et al. Drug Metab Dispos. 1991 Jan-Feb;19(1):222-6. Drug Metab Dispos. 1991. PMID: 1673403

3

Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation.

Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M. Engel G, et al. Among authors: hofmann u. Clin Pharmacol Ther. 1996 Jun;59(6):613-23. doi: 10.1016/S0009-9236(96)90001-6. Clin Pharmacol Ther. 1996. PMID: 8681486

4

In vitro interaction of codeine and diclofenac.

Ammon S, von Richter O, Hofmann U, Thon KP, Eichelbaum M, Mikus G. Ammon S, et al. Among authors: hofmann u. Drug Metab Dispos. 2000 Oct;28(10):1149-52. Drug Metab Dispos. 2000. PMID: 10997932

5

Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry.

Mürdter TE, Coller J, Claviez A, Schönberger F, Hofmann U, Dreger P, Schwab M. Mürdter TE, et al. Among authors: hofmann u. Clin Chem. 2001 Aug;47(8):1437-42. Clin Chem. 2001. PMID: 11468234 Clinical Trial.

6

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: hofmann u. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

7

Simple and sensitive method for the determination of celecoxib in human serum by high-performance liquid chromatography with fluorescence detection.

Schönberger F, Heinkele G, Mürdter TE, Brenner S, Klotz U, Hofmann U. Schönberger F, et al. Among authors: hofmann u. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Mar 5;768(2):255-60. doi: 10.1016/s1570-0232(01)00588-8. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 11888053

8

Cyclophosphamide pharmacokinetics and dose requirements in patients with renal insufficiency.

Haubitz M, Bohnenstengel F, Brunkhorst R, Schwab M, Hofmann U, Busse D. Haubitz M, et al. Among authors: hofmann u. Kidney Int. 2002 Apr;61(4):1495-501. doi: 10.1046/j.1523-1755.2002.00279.x. Kidney Int. 2002. PMID: 11918757 Free article.

9

Diclofenac does not interact with codeine metabolism in vivo: a study in healthy volunteers.

Ammon S, Marx C, Behrens C, Hofmann U, Mürdter T, Griese EU, Mikus G. Ammon S, et al. Among authors: hofmann u. BMC Clin Pharmacol. 2002 Feb 27;2:2. doi: 10.1186/1472-6904-2-2. BMC Clin Pharmacol. 2002. PMID: 11943073 Free PMC article. Clinical Trial.

10

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: hofmann u. Br J Clin Pharmacol. 2002 May;53(5):526-34. doi: 10.1046/j.1365-2125.2002.01591.x. Br J Clin Pharmacol. 2002. PMID: 11994059 Free PMC article. Clinical Trial.

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