Metcalf D - Search Results

1

A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency.

Verhagen AM, Wallace ME, Goradia A, Jones SA, Croom HA, Metcalf D, Collinge JE, Maxwell MJ, Hibbs ML, Alexander WS, Hilton DJ, Kile BT, Starr R. Verhagen AM, et al. Among authors: metcalf d. J Immunol. 2009 Feb 15;182(4):2020-9. doi: 10.4049/jimmunol.0803127. J Immunol. 2009. PMID: 19201855

2

Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis.

Cornish AL, Davey GM, Metcalf D, Purton JF, Corbin JE, Greenhalgh CJ, Darwiche R, Wu L, Nicola NA, Godfrey DI, Heath WR, Hilton DJ, Alexander WS, Starr R. Cornish AL, et al. Among authors: metcalf d. J Immunol. 2003 Jan 15;170(2):878-86. doi: 10.4049/jimmunol.170.2.878. J Immunol. 2003. PMID: 12517953

3

A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".

Tucker E, O'Donnell K, Fuchsberger M, Hilton AA, Metcalf D, Greig K, Sims NA, Quinn JM, Alexander WS, Hilton DJ, Kile BT, Tarlinton DM, Starr R. Tucker E, et al. Among authors: metcalf d. J Immunol. 2007 Dec 1;179(11):7514-22. doi: 10.4049/jimmunol.179.11.7514. J Immunol. 2007. PMID: 18025196

4

Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia.

Verhagen AM, de Graaf CA, Baldwin TM, Goradia A, Collinge JE, Kile BT, Metcalf D, Starr R, Hilton DJ. Verhagen AM, et al. Among authors: metcalf d. J Immunol. 2012 Jan 1;188(1):122-34. doi: 10.4049/jimmunol.1100942. Epub 2011 Nov 21. J Immunol. 2012. PMID: 22105998

5

The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.

Loughran SJ, Kruse EA, Hacking DF, de Graaf CA, Hyland CD, Willson TA, Henley KJ, Ellis S, Voss AK, Metcalf D, Hilton DJ, Alexander WS, Kile BT. Loughran SJ, et al. Among authors: metcalf d. Nat Immunol. 2008 Jul;9(7):810-9. doi: 10.1038/ni.1617. Epub 2008 May 25. Nat Immunol. 2008. PMID: 18500345

6

Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b).

Greenhalgh CJ, Bertolino P, Asa SL, Metcalf D, Corbin JE, Adams TE, Davey HW, Nicola NA, Hilton DJ, Alexander WS. Greenhalgh CJ, et al. Among authors: metcalf d. Mol Endocrinol. 2002 Jun;16(6):1394-406. doi: 10.1210/mend.16.6.0845. Mol Endocrinol. 2002. PMID: 12040024

7

Anomalous megakaryocytopoiesis in mice with mutations in the c-Myb gene.

Metcalf D, Carpinelli MR, Hyland C, Mifsud S, Dirago L, Nicola NA, Hilton DJ, Alexander WS. Metcalf D, et al. Blood. 2005 May 1;105(9):3480-7. doi: 10.1182/blood-2004-12-4806. Epub 2005 Jan 21. Blood. 2005. PMID: 15665109 Free article.

8

Suppressor of cytokine signaling-1 in T cells and macrophages is critical for preventing lethal inflammation.

Chong MM, Metcalf D, Jamieson E, Alexander WS, Kay TW. Chong MM, et al. Among authors: metcalf d. Blood. 2005 Sep 1;106(5):1668-75. doi: 10.1182/blood-2004-08-3049. Epub 2005 May 17. Blood. 2005. PMID: 15899915 Free article.

9

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity.

Fenner JE, Starr R, Cornish AL, Zhang JG, Metcalf D, Schreiber RD, Sheehan K, Hilton DJ, Alexander WS, Hertzog PJ. Fenner JE, et al. Among authors: metcalf d. Nat Immunol. 2006 Jan;7(1):33-9. doi: 10.1038/ni1287. Epub 2005 Nov 27. Nat Immunol. 2006. PMID: 16311601

10

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.

Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M, Hilton AA, Hyland CD, Smyth GK, Corbin JE, Metcalf D, Alexander WS, Hilton DJ. Majewski IJ, et al. Among authors: metcalf d. PLoS Biol. 2008 Apr 15;6(4):e93. doi: 10.1371/journal.pbio.0060093. PLoS Biol. 2008. PMID: 18416604 Free PMC article.

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