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Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.
Vu CB, Bemis JE, Disch JS, Ng PY, Nunes JJ, Milne JC, Carney DP, Lynch AV, Smith JJ, Lavu S, Lambert PD, Gagne DJ, Jirousek MR, Schenk S, Olefsky JM, Perni RB. Vu CB, et al. Among authors: gagne dj. J Med Chem. 2009 Mar 12;52(5):1275-83. doi: 10.1021/jm8012954. J Med Chem. 2009. PMID: 19199480
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH. Milne JC, et al. Among authors: gagne dj. Nature. 2007 Nov 29;450(7170):712-6. doi: 10.1038/nature06261. Nature. 2007. PMID: 18046409 Free PMC article.
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.
Smith JJ, Kenney RD, Gagne DJ, Frushour BP, Ladd W, Galonek HL, Israelian K, Song J, Razvadauskaite G, Lynch AV, Carney DP, Johnson RJ, Lavu S, Iffland A, Elliott PJ, Lambert PD, Elliston KO, Jirousek MR, Milne JC, Boss O. Smith JJ, et al. Among authors: gagne dj. BMC Syst Biol. 2009 Mar 10;3:31. doi: 10.1186/1752-0509-3-31. BMC Syst Biol. 2009. PMID: 19284563 Free PMC article.
Trust and trustworthy artificial intelligence: A research agenda for AI in the environmental sciences.
Bostrom A, Demuth JL, Wirz CD, Cains MG, Schumacher A, Madlambayan D, Bansal AS, Bearth A, Chase R, Crosman KM, Ebert-Uphoff I, Gagne DJ 2nd, Guikema S, Hoffman R, Johnson BB, Kumler-Bonfanti C, Lee JD, Lowe A, McGovern A, Przybylo V, Radford JT, Roth E, Sutter C, Tissot P, Roebber P, Stewart JQ, White M, Williams JK. Bostrom A, et al. Among authors: gagne dj 2nd. Risk Anal. 2024 Jun;44(6):1498-1513. doi: 10.1111/risa.14245. Epub 2023 Nov 8. Risk Anal. 2024. PMID: 37939398
Community annotation and bioinformatics workforce development in concert--Little Skate Genome Annotation Workshops and Jamborees.
Wang Q, Arighi CN, King BL, Polson SW, Vincent J, Chen C, Huang H, Kingham BF, Page ST, Rendino MF, Thomas WK, Udwary DW, Wu CH; North East Bioinformatics Collaborative Curation Team. Wang Q, et al. Database (Oxford). 2012 Mar 20;2012:bar064. doi: 10.1093/database/bar064. Print 2012. Database (Oxford). 2012. PMID: 22434832 Free PMC article.
46 results