Sluis-Cremer N - Search Results

1

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.

Ambrose Z, Herman BD, Sheen CW, Zelina S, Moore KL, Tachedjian G, Nissley DV, Sluis-Cremer N. Ambrose Z, et al. J Virol. 2009 Apr;83(8):3826-33. doi: 10.1128/JVI.01968-08. Epub 2009 Feb 4. J Virol. 2009. PMID: 19193782 Free PMC article.

2

Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors.

Sluis-Cremer N, Arion D, Parniak MA. Sluis-Cremer N, et al. Mol Pharmacol. 2002 Aug;62(2):398-405. doi: 10.1124/mol.62.2.398. Mol Pharmacol. 2002. PMID: 12130693

3

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules.

Sluis-Cremer N, Tachedjian G. Sluis-Cremer N, et al. Eur J Biochem. 2002 Nov;269(21):5103-11. doi: 10.1046/j.1432-1033.2002.03216.x. Eur J Biochem. 2002. PMID: 12392542 Free article. Review.

4

Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation.

Sluis-Cremer N, Arion D, Abram ME, Parniak MA. Sluis-Cremer N, et al. Int J Biochem Cell Biol. 2004 Sep;36(9):1836-47. doi: 10.1016/j.biocel.2004.02.020. Int J Biochem Cell Biol. 2004. PMID: 15183348

5

Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding.

Sluis-Cremer N, Temiz NA, Bahar I. Sluis-Cremer N, et al. Curr HIV Res. 2004 Oct;2(4):323-32. doi: 10.2174/1570162043351093. Curr HIV Res. 2004. PMID: 15544453 Free PMC article. Review.

6

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation.

Tachedjian G, Moore KL, Goff SP, Sluis-Cremer N. Tachedjian G, et al. FEBS Lett. 2005 Jan 17;579(2):379-84. doi: 10.1016/j.febslet.2004.11.099. FEBS Lett. 2005. PMID: 15642347 Free article.

7

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.

Tachedjian G, Radzio J, Sluis-Cremer N. Tachedjian G, et al. Proteins. 2005 Jul 1;60(1):5-13. doi: 10.1002/prot.20480. Proteins. 2005. PMID: 15852304

8

Stereo-selectivity of HIV-1 reverse transcriptase toward isomers of thymidine-5'-O-1-thiotriphosphate.

Radzio J, Sluis-Cremer N. Radzio J, et al. Protein Sci. 2005 Jul;14(7):1929-33. doi: 10.1110/ps.051445605. Epub 2005 Jun 3. Protein Sci. 2005. PMID: 15937285 Free PMC article.

9

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

Srivastava S, Sluis-Cremer N, Tachedjian G. Srivastava S, et al. Curr Pharm Des. 2006;12(15):1879-94. doi: 10.2174/138161206776873590. Curr Pharm Des. 2006. PMID: 16724954 Review.

10

Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization.

Sluis-Cremer N, Hamamouch N, San Félix A, Velazquez S, Balzarini J, Camarasa MJ. Sluis-Cremer N, et al. J Med Chem. 2006 Aug 10;49(16):4834-41. doi: 10.1021/jm0604575. J Med Chem. 2006. PMID: 16884295

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