Sabatini DM - Search Results

1

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.

Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P, Sabatini DM. Jones TR, et al. Among authors: sabatini dm. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1826-31. doi: 10.1073/pnas.0808843106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188593 Free PMC article.

2

Systematic genome-wide screens of gene function.

Carpenter AE, Sabatini DM. Carpenter AE, et al. Among authors: sabatini dm. Nat Rev Genet. 2004 Jan;5(1):11-22. doi: 10.1038/nrg1248. Nat Rev Genet. 2004. PMID: 14708012 Review. No abstract available.

3

Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens.

Bailey SN, Sabatini DM, Stockwell BR. Bailey SN, et al. Among authors: sabatini dm. Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16144-9. doi: 10.1073/pnas.0404425101. Epub 2004 Nov 8. Proc Natl Acad Sci U S A. 2004. PMID: 15534212 Free PMC article.

4

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells.

Wheeler DB, Bailey SN, Guertin DA, Carpenter AE, Higgins CO, Sabatini DM. Wheeler DB, et al. Among authors: sabatini dm. Nat Methods. 2004 Nov;1(2):127-32. doi: 10.1038/nmeth711. Epub 2004 Oct 21. Nat Methods. 2004. PMID: 15782175

5

Cell microarrays and RNA interference chip away at gene function.

Wheeler DB, Carpenter AE, Sabatini DM. Wheeler DB, et al. Among authors: sabatini dm. Nat Genet. 2005 Jun;37 Suppl:S25-30. doi: 10.1038/ng1560. Nat Genet. 2005. PMID: 15920526 Review.

6

Microarrays of lentiviruses for gene function screens in immortalized and primary cells.

Bailey SN, Ali SM, Carpenter AE, Higgins CO, Sabatini DM. Bailey SN, et al. Among authors: sabatini dm. Nat Methods. 2006 Feb;3(2):117-22. doi: 10.1038/nmeth848. Nat Methods. 2006. PMID: 16432521

7

Building mammalian signalling pathways with RNAi screens.

Moffat J, Sabatini DM. Moffat J, et al. Among authors: sabatini dm. Nat Rev Mol Cell Biol. 2006 Mar;7(3):177-87. doi: 10.1038/nrm1860. Nat Rev Mol Cell Biol. 2006. PMID: 16496020 Review.

8

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.

Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE. Moffat J, et al. Among authors: sabatini dm. Cell. 2006 Mar 24;124(6):1283-98. doi: 10.1016/j.cell.2006.01.040. Cell. 2006. PMID: 16564017 Free article.

9

Genome-scale loss-of-function screening with a lentiviral RNAi library.

Root DE, Hacohen N, Hahn WC, Lander ES, Sabatini DM. Root DE, et al. Among authors: sabatini dm. Nat Methods. 2006 Sep;3(9):715-9. doi: 10.1038/nmeth924. Nat Methods. 2006. PMID: 16929317 Review.

10

Minimizing the risk of reporting false positives in large-scale RNAi screens.

Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prévôt B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R. Echeverri CJ, et al. Among authors: sabatini dm. Nat Methods. 2006 Oct;3(10):777-9. doi: 10.1038/nmeth1006-777. Nat Methods. 2006. PMID: 16990807

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